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    nfyc-1 Nuclear transcription factor Y subunit nfyc-1 [ Caenorhabditis elegans ]

    Gene ID: 173385, updated on 9-Dec-2024

    Summary

    Official Symbol
    nfyc-1
    Official Full Name
    Nuclear transcription factor Y subunit nfyc-1
    Primary source
    WormBase:WBGene00017742
    Locus tag
    CELE_F23F1.1
    See related
    AllianceGenome:WB:WBGene00017742
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables DNA-binding transcription repressor activity. Involved in negative regulation of transcription by RNA polymerase II and tissue development. Located in cytoplasm and perikaryon. Is expressed in several structures, including gonad. Orthologous to human NFYC (nuclear transcription factor Y subunit gamma). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See nfyc-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (43907..44917)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Saposin B-type domain-containing protein Neighboring gene Reverse transcriptase domain-containing protein Neighboring gene putative 26S proteasome regulatory subunit 10B Neighboring gene RNA polymerase I associated factor, A49-like protein Neighboring gene Nucleolus and neural progenitor protein-like N-terminal domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables DNA-binding transcription repressor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    contributes_to RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of CCAAT-binding factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perikaryon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Nuclear transcription factor Y subunit nfyc-1
    NP_001300537.1
    • Confirmed by transcript evidence
    NP_493645.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      43907..44917
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061244.8NP_493645.1  Nuclear transcription factor Y subunit nfyc-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493645.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A0K3AWV9, O17072
      Conserved Domains (1) summary
      COG5208
      Location:65206
      HAP5; CCAAT-binding factor, subunit C [Transcription]
    2. NM_001313608.3NP_001300537.1  Nuclear transcription factor Y subunit nfyc-1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AWV9
      Conserved Domains (1) summary
      COG5208
      Location:30171
      HAP5; CCAAT-binding factor, subunit C [Transcription]