U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rpl-35A Large ribosomal subunit protein eL33 [ Caenorhabditis elegans ]

    Gene ID: 174166, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rpl-35A
    Official Full Name
    Large ribosomal subunit protein eL33
    Primary source
    WormBase:WBGene00004447
    Locus tag
    CELE_F10E7.7
    See related
    AllianceGenome:WB:WBGene00004447
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and ribosomal large subunit biogenesis. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 5. Orthologous to human RPL35A (ribosomal protein L35a). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rpl-35A in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (7105563..7106316)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Methylmalonic aciduria type A homolog, mitochondrial Neighboring gene DUF3402 domain-containing protein;Far11/STRP C-terminal domain-containing protein Neighboring gene Amino acid permease/ SLC12A domain-containing protein Neighboring gene Ribosome assembly factor mrt4

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. rRNA intermediates coordinate the formation of nucleolar vacuoles in C. elegans. Xu D, et al. Cell Rep, 2023 Aug 29. PMID 37537842
    2. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Kamath RS, et al. Nature, 2003 Jan 16. PMID 12529635
    3. RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans. Akay A, et al. Open Biol, 2013 Nov 20. PMID 24258276, Free PMC Article
    4. Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes. Arnold A, et al. Nucleic Acids Res, 2014 Dec 1. PMID 25378320, Free PMC Article
    5. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Large ribosomal subunit protein eL33
    NP_495468.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7105563..7106316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063067.7 → NP_495468.1  Large ribosomal subunit protein eL33 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495468.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P49180
      Conserved Domains (1) summary
      pfam01247
      Location:18 → 117
      Ribosomal_L35Ae; Ribosomal protein L35Ae
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P49180.3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.