HTA9 histone H2A protein 9 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: HTA9
Official Full Name: histone H2A protein 9
Primary source: TAIR:AT1G52740
Locus tag: AT1G52740
See related: Araport:AT1G52740
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F14G24.1; F14G24_1; histone H2A protein 9
Summary: Encodes HTA9, a histone H2A protein. Loss of all H2A.Z (triple mutant with HTA8 and HTA11) results in a reduction in DNA methylation of transposons but not that of genes. Loss of H2A.Z causes misregulation of many genes involved in the response to developmental and environmental cues, and that these genes tend to have high levels of gene-body H2A.Z.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See HTA9 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 2

Sequence:: Chromosome: 1; NC_003070.9 (19645236..19646485)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Histone variant H2A.Z is required for plant salt response by regulating gene transcription.
Title: Histone variant H2A.Z is required for plant salt response by regulating gene transcription.
Histone chaperones AtChz1A and AtChz1B are required for H2A.Z deposition and interact with the SWR1 chromatin-remodeling complex in Arabidopsis thaliana.
Title: Histone chaperones AtChz1A and AtChz1B are required for H2A.Z deposition and interact with the SWR1 chromatin-remodeling complex in Arabidopsis thaliana.
Data suggests an antagonistic role between H2A.Z and H3K4me3 in the regulation of the expression of anthocyanin biosynthetic genes, highlighting a role of chromatin in gene regulation and reflecting the complexity of gene regulatory mechanisms.s [H2A.Z] [HTA9]
Title: Epigenetic regulation of anthocyanin biosynthesis by an antagonistic interaction between H2A.Z and H3K4me3.
YAF9A binds FLC chromatin and that YAF9 proteins regulate FLC expression by modulating the acetylation levels of H2A.Z and H4 but not H2A.Z deposition.[H2A.z]
Title: Arabidopsis YAF9 histone readers modulate flowering time through NuA4-complex-dependent H4 and H2A.Z histone acetylation at FLC chromatin.
MBD9 is a SWR1-C interacting protein required for H2A.Z deposition at a subset of actively transcribing genes. [H2A.Z]
Title: Arabidopsis SWR1-associated protein methyl-CpG-binding domain 9 is required for histone H2A.Z deposition.
H2A.z mediates different aspects of chromatin function. Gene expression changes in plant responsiveness to environmental cues also involve H2A.Z, in particular in temperature sensing and in the flowering response to ambient temperature. [H2A.Z]
Title: H2A.Z mediates different aspects of chromatin function and modulates flowering responses in Arabidopsis.
The induction of ethylene-responsive genes does not require immediate modulation of H3K4me3 and H3K27me3 and dissociation of LHP1 and H2A.Z from the targets.[H2A.Z]
Title: The role of histone methylation and H2A.Z occupancy during rapid activation of ethylene responsive genes.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_104152.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info
enables structural constituent of chromatin	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within defense response to bacterium	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of flower development	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of gene expression	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to temperature stimulus	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in plant-type vacuole	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: histone H2A protein 9

NP_175683.1

histone H2A protein 9 (HTA9); FUNCTIONS IN: DNA binding; INVOLVED IN: detection of temperature stimulus, defense response to bacterium, regulation of flower development; LOCATED IN: vacuole; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Histone H2A (InterPro:IPR002119), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: histone H2A 11 (TAIR:AT3G54560.1); Has 3910 Blast hits to 3905 proteins in 353 species: Archae - 0; Bacteria - 0; Metazoa - 2573; Fungi - 292; Plants - 612; Viruses - 4; Other Eukaryotes - 429 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

19645236..19646485

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_104152.4 → NP_175683.1 histone H2A protein 9 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_175683.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9C944

UniProtKB/TrEMBL

A0A178WNI4, A0A5S9WLR5

Conserved Domains (1) summary

PLN00154
Location:1 → 134

PLN00154; histone H2A; Provisional