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    DIN4 Transketolase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820547, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DIN4
    Official Full Name
    Transketolase family protein
    Primary source
    TAIR:AT3G13450
    Locus tag
    AT3G13450
    See related
    Araport:AT3G13450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    DARK INDUCIBLE 4
    Summary
    branched chain alpha-keto acid dehydrogenase E1 beta
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    Genomic context

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    See DIN4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (4382198..4384436, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene pseudo Neighboring gene TATA binding protein 1 Neighboring gene evolutionarily conserved C-terminal region 2 Neighboring gene TCP-1/cpn60 chaperonin family protein Neighboring gene nuclear polyadenylated RNA-binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of cDNA clones for the e1beta and E2 subunits of the branched-chain alpha-ketoacid dehydrogenase complex in Arabidopsis. Fujiki Y, et al. J Biol Chem, 2000 Feb 25. PMID 10681595
    2. The Impact of the Branched-Chain Ketoacid Dehydrogenase Complex on Amino Acid Homeostasis in Arabidopsis. Peng C, et al. Plant Physiol, 2015 Nov. PMID 25986129, Free PMC Article
    3. Multiple signaling pathways in gene expression during sugar starvation. Pharmacological analysis of din gene expression in suspension-cultured cells of Arabidopsis. Fujiki Y, et al. Plant Physiol, 2000 Nov. PMID 11080291, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_112191.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within branched-chain amino acid catabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in cellular response to sucrose starvation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to absence of light IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to sucrose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Transketolase family protein
    NP_187954.1
    • DARK INDUCIBLE 4 (DIN4); FUNCTIONS IN: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity, catalytic activity; INVOLVED IN: response to light stimulus, response to sucrose stimulus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Transketolase, C-terminal (InterPro:IPR005476), Transketolase-like, C-terminal (InterPro:IPR015941), Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II (InterPro:IPR009014), Transketolase-like, pyrimidine-binding domain (InterPro:IPR005475); BEST Arabidopsis thaliana protein match is: branched-chain alpha-keto acid decarboxylase E1 beta subunit (TAIR:AT1G55510.1); Has 16402 Blast hits to 16393 proteins in 2657 species: Archae - 210; Bacteria - 10668; Metazoa - 495; Fungi - 224; Plants - 385; Viruses - 0; Other Eukaryotes - 4420 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4382198..4384436 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112191.3 → NP_187954.1  Transketolase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187954.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LDY2
      UniProtKB/TrEMBL
      A0A178VJU1, A0A5S9XC02, A0A654F6R1
      Conserved Domains (1) summary
      PTZ00182
      Location:23 → 356
      PTZ00182; 3-methyl-2-oxobutanate dehydrogenase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LDY2.1

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