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    GA2OX7 gibberellin 2-oxidase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841518, updated on 14-Nov-2024

    Summary

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    Official Symbol
    GA2OX7
    Official Full Name
    gibberellin 2-oxidase 7
    Primary source
    TAIR:AT1G50960
    Locus tag
    AT1G50960
    See related
    Araport:AT1G50960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA GIBBERELLIN 2-OXIDASE 7; ATGA2OX7; F8A12.18; F8A12_18; gibberellin 2-oxidase 7
    Summary
    Encodes a protein with gibberellin 2-oxidase activity which acts specifically on C-20 gibberellins. DDF1 binds to GA2OX7 and regulates its expression in response to salt stress.
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    Genomic context

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    See GA2OX7 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (18889473..18891838)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene electron transfer flavoprotein alpha Neighboring gene ncRNA Neighboring gene protein disulfide-isomerase 5-like protein (DUF1692) Neighboring gene ncRNA Neighboring gene Membrane trafficking VPS53 family protein Neighboring gene F-box/RNI-like/FBD-like domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The DDF1 transcriptional activator upregulates expression of a gibberellin-deactivating gene, GA2ox7, under high-salinity stress in Arabidopsis. Magome H, et al. Plant J, 2008 Nov. PMID 18643985
    2. Overexpression of a novel class of gibberellin 2-oxidases decreases gibberellin levels and creates dwarf plants. Schomburg FM, et al. Plant Cell, 2003 Jan. PMID 12509528, Free PMC Article
    3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GA2ox7 is upregulated DDF1 under high-salinity stress which causes gibberellin deficiency in DDF1-overexpressing plants.
      Title: The DDF1 transcriptional activator upregulates expression of a gibberellin-deactivating gene, GA2ox7, under high-salinity stress in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables gibberellin 2-beta-dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables gibberellin 2-beta-dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gibberellin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within gibberellin metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    gibberellin 2-oxidase 7
    NP_175509.1
    • gibberellin 2-oxidase 7 (GA2OX7); FUNCTIONS IN: C-20 gibberellin 2-beta-dioxygenase activity; INVOLVED IN: response to salt stress, gibberellin biosynthetic process, gibberellin metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: central cell, hypocotyl; CONTAINS InterPro DOMAIN/s: Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 8 (TAIR:AT4G21200.1); Has 8324 Blast hits to 8283 proteins in 985 species: Archae - 0; Bacteria - 1088; Metazoa - 111; Fungi - 933; Plants - 4816; Viruses - 0; Other Eukaryotes - 1376 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      18889473..18891838
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103976.2 → NP_175509.1  gibberellin 2-oxidase 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175509.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9C6I4
      UniProtKB/TrEMBL
      A0A178W2P5, A0A5S9WND3, A0A7G2E339
      Conserved Domains (1) summary
      PLN02984
      Location:3 → 336
      PLN02984; oxidoreductase, 2OG-Fe(II) oxygenase family protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C6I4.1

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