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    GLDP1 glycine decarboxylase P-protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829438, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLDP1
    Official Full Name
    glycine decarboxylase P-protein 1
    Primary source
    TAIR:AT4G33010
    Locus tag
    AT4G33010
    See related
    Araport:AT4G33010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtGLDP1; F4I10.7; glycine decarboxylase P-protein 1
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    Genomic context

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    See GLDP1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    14
    Sequence:
    Chromosome: 4; NC_003075.7 (15926652..15931422, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene calcineurin B-like protein 10 Neighboring gene ZIP metal ion transporter family Neighboring gene sulfoquinovosyldiacylglycerol 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Deletion of glycine decarboxylase in Arabidopsis is lethal under nonphotorespiratory conditions. Engel N, et al. Plant Physiol, 2007 Jul. PMID 17496108, Free PMC Article
    2. Redox-Regulation of Photorespiration through Mitochondrial Thioredoxin o1. Reinholdt O, et al. Plant Physiol, 2019 Oct. PMID 31413204, Free PMC Article
    3. Leaf proteome responses of Arabidopsis thaliana exposed to mild cadmium stress. Semane B, et al. J Plant Physiol, 2010 Mar 1. PMID 20005002
    4. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Lee CP, et al. Mol Cell Proteomics, 2008 Jul. PMID 18385124
    5. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Redox-Regulation of Photorespiration through Mitochondrial Thioredoxin o1.
      Title: Redox-Regulation of Photorespiration through Mitochondrial Thioredoxin o1.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001125634.1
    NM_119455.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycine dehydrogenase (decarboxylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in glycine catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within glycine catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cadmium ion IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast thylakoid HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    glycine decarboxylase P-protein 1
    NP_001119106.1
    • glycine decarboxylase P-protein 1 (GLDP1); FUNCTIONS IN: glycine dehydrogenase (decarboxylating) activity, protein binding; INVOLVED IN: glycine catabolic process, response to cadmium ion, glycine decarboxylation via glycine cleavage system; LOCATED IN: mitochondrion, apoplast, glycine cleavage complex, chloroplast; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Glycine cleavage system P-protein-like (InterPro:IPR020581), Glycine cleavage system P-protein (InterPro:IPR003437), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Glycine cleavage system P-protein, N-terminal (InterPro:IPR020580); BEST Arabidopsis thaliana protein match is: glycine decarboxylase P-protein 2 (TAIR:AT2G26080.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_195027.1
    • glycine decarboxylase P-protein 1 (GLDP1); FUNCTIONS IN: glycine dehydrogenase (decarboxylating) activity, protein binding; INVOLVED IN: glycine catabolic process, response to cadmium ion, glycine decarboxylation via glycine cleavage system; LOCATED IN: mitochondrion, apoplast, glycine cleavage complex, chloroplast, chloroplast envelope; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Glycine cleavage system P-protein (InterPro:IPR003437), Glycine cleavage system P-protein-like (InterPro:IPR020581), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Glycine cleavage system P-protein, N-terminal (InterPro:IPR020580); BEST Arabidopsis thaliana protein match is: glycine decarboxylase P-protein 2 (TAIR:AT2G26080.1); Has 12463 Blast hits to 11454 proteins in 1943 species: Archae - 255; Bacteria - 5318; Metazoa - 139; Fungi - 214; Plants - 99; Viruses - 0; Other Eukaryotes - 6438 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      15926652..15931422 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119455.3 → NP_195027.1  glycine decarboxylase P-protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195027.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82642, Q8GTY1, Q8VZF0, Q94B78
      UniProtKB/TrEMBL
      A0A178UTF1, A0A5S9XY43, A0A7G2F5N5
      Conserved Domains (1) summary
      PLN02414
      Location:1 → 1037
      PLN02414; glycine dehydrogenase (decarboxylating)

    2. NM_001125634.1 → NP_001119106.1  glycine decarboxylase P-protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119106.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2F5N5, B3H5Y8
      Conserved Domains (3) summary
      PLN02414
      Location:1 → 974
      PLN02414; glycine dehydrogenase (decarboxylating)
      COG1003
      Location:518 → 975
      GcvP2; Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain [Amino acid transport and metabolism]
      cl18945
      Location:81 → 508
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94B78.2

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