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    CHL chloroplastic lipocalin [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823942, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CHL
    Official Full Name
    chloroplastic lipocalin
    Primary source
    TAIR:AT3G47860
    Locus tag
    AT3G47860
    See related
    Araport:AT3G47860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    chloroplastic lipocalin
    Summary
    Encodes a chloroplastic lipocalin AtCHL. Located in thylakoid lumen. Involved in the protection of thylakoidal membrane lipids against reactive oxygen species, especially singlet oxygen, produced upon excess light.
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    Genomic context

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    See CHL in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (17656602..17658353, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene tRNA (Ile)-lysidine synthase Neighboring gene LOB domain-containing protein 27 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Plastid Lipocalin LCNP Is Required for Sustained Photoprotective Energy Dissipation in Arabidopsis. Malnoë A, et al. Plant Cell, 2018 Jan. PMID 29233855, Free PMC Article
    2. The chloroplastic lipocalin AtCHL prevents lipid peroxidation and protects Arabidopsis against oxidative stress. Levesque-Tremblay G, et al. Plant J, 2009 Nov. PMID 19674405
    3. Arabidopsis lipocalins AtCHL and AtTIL have distinct but overlapping functions essential for lipid protection and seed longevity. Boca S, et al. Plant Cell Environ, 2014 Feb. PMID 23837879
    4. New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy. Peltier JB, et al. J Biol Chem, 2004 Nov 19. PMID 15322131
    5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtTIL and AtCHL have overlapping functions in lipid protection which are essential for stress resistance and survival.
      Title: Arabidopsis lipocalins AtCHL and AtTIL have distinct but overlapping functions essential for lipid protection and seed longevity.
    2. AtCHL is localized in the thylakoid lumen, alleviates membrane lipid peroxidation, and increases tolerance towards oxidative stress induced by paraquat or drought treatment.
      Title: The chloroplastic lipocalin AtCHL prevents lipid peroxidation and protects Arabidopsis against oxidative stress.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_114656.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables small molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of fatty acid oxidation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within photoprotection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to high light intensity IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to high light intensity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to paraquat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to water deprivation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in seed maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast thylakoid membrane HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in thylakoid lumen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chloroplastic lipocalin
    NP_190370.1
    • chloroplastic lipocalin (CHL); FUNCTIONS IN: binding; INVOLVED IN: response to oxidative stress; LOCATED IN: thylakoid lumen, chloroplast thylakoid membrane, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Lipocalin-like (InterPro:IPR013208), Lipocalin conserved site (InterPro:IPR022272), Calycin (InterPro:IPR012674), Calycin-like (InterPro:IPR011038); Has 184 Blast hits to 184 proteins in 68 species: Archae - 0; Bacteria - 14; Metazoa - 66; Fungi - 0; Plants - 91; Viruses - 0; Other Eukaryotes - 13 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17656602..17658353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114656.4 → NP_190370.1  chloroplastic lipocalin [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190370.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9STS7
      UniProtKB/TrEMBL
      A0A178VKZ0, A0A5S9XIW2
      Conserved Domains (1) summary
      cl10502
      Location:126 → 266
      lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9STS7.1

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