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    CIPK15 CBL-interacting protein kinase 15 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830556, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CIPK15
    Official Full Name
    CBL-interacting protein kinase 15
    Primary source
    TAIR:AT5G01810
    Locus tag
    AT5G01810
    See related
    Araport:AT5G01810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPK10; CBL-interacting protein kinase 15; PKS3; PROTEIN KINASE 10; SERINE/THREONINE PROTEIN KINASE 10; SIP2; SMALL AND BASIC INTRINSIC PROTEIN 2; SNF1-RELATED PROTEIN KINASE 3.1; SNRK3.1; SOS3-INTERACTING PROTEIN 2; T20L15.80; T20L15_80
    Summary
    Encodes a CBL-interacting serine/threonine protein kinase, also has similarities to SOS2 kinase.
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    Genomic context

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    See CIPK15 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (309374..312097)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene saposin B domain-containing protein Neighboring gene serine/threonine protein kinase 1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CIPK15-mediated inhibition of NH(4)(+) transport protects Arabidopsis from submergence. Chen YN, et al. Heliyon, 2023 Sep. PMID 37810036, Free PMC Article
    2. Feedback inhibition of AMT1 NH(4)(+)-transporters mediated by CIPK15 kinase. Chen HY, et al. BMC Biol, 2020 Dec 14. PMID 33317525, Free PMC Article
    3. Role of an Arabidopsis AP2/EREBP-type transcriptional repressor in abscisic acid and drought stress responses. Song CP, et al. Plant Cell, 2005 Aug. PMID 15994908, Free PMC Article
    4. A calcium sensor and its interacting protein kinase are global regulators of abscisic acid signaling in Arabidopsis. Guo Y, et al. Dev Cell, 2002 Aug. PMID 12194854
    5. A novel domain in the protein kinase SOS2 mediates interaction with the protein phosphatase 2C ABI2. Ohta M, et al. Proc Natl Acad Sci U S A, 2003 Sep 30. PMID 14504388, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Feedback inhibition of AMT1 NH4(+)-transporters mediated by CIPK15 kinase.
      Title: Feedback inhibition of AMT1 NH(4)(+)-transporters mediated by CIPK15 kinase.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001036743.1
    NM_001203274.1
    NM_120259.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein kinase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within abscisic acid-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in response to flooding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CBL-interacting protein kinase 15
    NP_001031820.1
    • CBL-interacting protein kinase 15 (CIPK15); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: SOS3-interacting protein 1 (TAIR:AT5G58380.1); Has 132404 Blast hits to 130096 proteins in 4624 species: Archae - 185; Bacteria - 15280; Metazoa - 48696; Fungi - 13190; Plants - 32556; Viruses - 526; Other Eukaryotes - 21971 (source: NCBI BLink).
    NP_001190203.1
    • CBL-interacting protein kinase 15 (CIPK15); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: CBL-interacting protein kinase 20 (TAIR:AT5G45820.1).
    NP_195801.1
    • CBL-interacting protein kinase 15 (CIPK15); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: SOS3-interacting protein 1 (TAIR:AT5G58380.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      309374..312097
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120259.4 → NP_195801.1  CBL-interacting protein kinase 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195801.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P92937, Q0D240, Q0WQ20, Q9LZW5
      UniProtKB/TrEMBL
      A0A178UHH3
      Conserved Domains (3) summary
      cd12195
      Location:305 → 413
      CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases
      smart00220
      Location:12 → 266
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14663
      Location:11 → 265
      STKc_SnRK3; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 3

    2. NM_001036743.1 → NP_001031820.1  CBL-interacting protein kinase 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031820.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P92937, Q0D240, Q0WQ20, Q9LZW5
      UniProtKB/TrEMBL
      A0A178UHH3
      Conserved Domains (3) summary
      cd12195
      Location:305 → 413
      CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases
      smart00220
      Location:12 → 266
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14663
      Location:11 → 265
      STKc_SnRK3; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 3

    3. NM_001203274.1 → NP_001190203.1  CBL-interacting protein kinase 15 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190203.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UHH3, F4KAV7
      Conserved Domains (3) summary
      cd12195
      Location:286 → 368
      CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases
      smart00220
      Location:12 → 266
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14663
      Location:11 → 265
      STKc_SnRK3; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P92937.2

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