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    SOS4 pfkB-like carbohydrate kinase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 833763, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SOS4
    Official Full Name
    pfkB-like carbohydrate kinase family protein
    Primary source
    TAIR:AT5G37850
    Locus tag
    AT5G37850
    See related
    Araport:AT5G37850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSOS4; K18L3.1; K18L3_1; SALT OVERLY SENSITIVE 4
    Summary
    Encodes a pyridoxal kinase required for root hair development. Mutants are hypersensitive to Na+, K+ and Li+.
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    Genomic context

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    See SOS4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Sequence:
    Chromosome: 5; NC_003076.8 (15065300..15069094)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene oxoprolinase 1 Neighboring gene plastid movement impaired protein Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning and characterization of Arabidopsis thaliana pyridoxal kinase. Lum HK, et al. Planta, 2002 Sep. PMID 12244454
    2. SOS4, a pyridoxal kinase gene, is required for root hair development in Arabidopsis. Shi H, et al. Plant Physiol, 2002 Jun. PMID 12068103, Free PMC Article
    3. The Arabidopsis salt overly sensitive 4 mutants uncover a critical role for vitamin B6 in plant salt tolerance. Shi H, et al. Plant Cell, 2002 Mar. PMID 11910005, Free PMC Article
    4. Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway. González E, et al. Plant Physiol, 2007 Nov. PMID 17873088, Free PMC Article
    5. Interactome analysis reveals versatile functions of Arabidopsis COLD SHOCK DOMAIN PROTEIN 3 in RNA processing within the nucleus and cytoplasm. Kim MH, et al. Cell Stress Chaperones, 2013 Jul. PMID 23334891, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The phenotype, stress responses, vitamer levels, and regulation of the vitamin B6 pathway genes in Arabidopsis plants mutant in pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and SALT OVERLY SENSITIVE4 (SOS4) are reported.
      Title: Vitamer levels, stress response, enzyme activity, and gene regulation of Arabidopsis lines mutant in the pyridoxine/pyridoxamine 5'-phosphate oxidase (PDX3) and the pyridoxal kinase (SOS4) genes involved in the vitamin B6 salvage pathway.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001085208.2
    NM_001203503.1
    NM_123144.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables pyridoxal kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pyridoxal kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyridoxal kinase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within hyperosmotic salinity response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pyridoxal 5'-phosphate salvage IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in pyridoxal 5'-phosphate salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pyridoxine biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within trichoblast differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    pfkB-like carbohydrate kinase family protein
    NP_001078677.1
    • SALT OVERLY SENSITIVE 4 (SOS4); FUNCTIONS IN: pyridoxal kinase activity, kinase activity; INVOLVED IN: pyridoxine biosynthetic process, hyperosmotic salinity response, trichoblast differentiation, pyridoxal 5'-phosphate salvage; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase (InterPro:IPR004625), Phosphomethylpyrimidine kinase type-1 (InterPro:IPR013749); BEST Arabidopsis thaliana protein match is: thiamin biosynthesis protein, putative (TAIR:AT1G22940.1); Has 6118 Blast hits to 6115 proteins in 1907 species: Archae - 81; Bacteria - 5074; Metazoa - 195; Fungi - 190; Plants - 75; Viruses - 0; Other Eukaryotes - 503 (source: NCBI BLink).
    NP_001190432.1
    • SALT OVERLY SENSITIVE 4 (SOS4); FUNCTIONS IN: pyridoxal kinase activity, kinase activity; INVOLVED IN: pyridoxine biosynthetic process, hyperosmotic salinity response, trichoblast differentiation, pyridoxal 5'-phosphate salvage; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase (InterPro:IPR004625), Phosphomethylpyrimidine kinase type-1 (InterPro:IPR013749).
    NP_198601.2
    • SALT OVERLY SENSITIVE 4 (SOS4); FUNCTIONS IN: pyridoxal kinase activity, kinase activity; INVOLVED IN: pyridoxine biosynthetic process, hyperosmotic salinity response, trichoblast differentiation, pyridoxal 5'-phosphate salvage; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate (active vitamin B6) biosynthesis, pyridoxal kinase (InterPro:IPR004625), Phosphomethylpyrimidine kinase type-1 (InterPro:IPR013749); BEST Arabidopsis thaliana protein match is: thiamin biosynthesis protein, putative (TAIR:AT1G22940.1); Has 6182 Blast hits to 6179 proteins in 1931 species: Archae - 81; Bacteria - 5137; Metazoa - 195; Fungi - 190; Plants - 75; Viruses - 0; Other Eukaryotes - 504 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      15065300..15069094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344222.1 → NP_001331291.1  pfkB-like carbohydrate kinase family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W1X2, Q94EN4, Q9FKE1
      UniProtKB/TrEMBL
      A0A178UIH6, A0A5S9YB57
      Conserved Domains (1) summary
      PLN02978
      Location:2 → 309
      PLN02978; pyridoxal kinase

    2. NM_001085208.2 → NP_001078677.1  pfkB-like carbohydrate kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078677.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W1X2, Q94EN4, Q9FKE1
      UniProtKB/TrEMBL
      A0A178UIH6, A0A5S9YB57
      Conserved Domains (1) summary
      PLN02978
      Location:2 → 309
      PLN02978; pyridoxal kinase

    3. NM_123144.4 → NP_198601.2  pfkB-like carbohydrate kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198601.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W1X2
      Conserved Domains (1) summary
      PLN02978
      Location:36 → 343
      PLN02978; pyridoxal kinase

    4. NM_001203503.1 → NP_001190432.1  pfkB-like carbohydrate kinase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190432.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4K8N1
      Conserved Domains (1) summary
      PLN02978
      Location:36 → 315
      PLN02978; pyridoxal kinase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W1X2.2

    Gene LinkOut

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