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    UBC6 ubiquitin-conjugating enzyme 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819211, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBC6
    Official Full Name
    ubiquitin-conjugating enzyme 6
    Primary source
    TAIR:AT2G46030
    Locus tag
    AT2G46030
    See related
    Araport:AT2G46030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T3F17.32; ubiquitin-conjugating enzyme 6
    Summary
    Ubiquitin conjugating enzyme E2
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    Genomic context

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    See UBC6 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (18932019..18934138, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ribosomal RNA small subunit methyltransferase G Neighboring gene ncRNA Neighboring gene LDL receptor wingless signaling/trafficking chaperone Neighboring gene transcription regulatory protein SNF2 Neighboring gene ARID/BRIGHT AND ELM2 DNA-binding domain-containing protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. UBC6, a ubiquitin-conjugating enzyme, participates in secondary cell wall thickening in the inflorescence stem of Arabidopsis. Wang Q, et al. Plant Physiol Biochem, 2023 Dec. PMID 37944242
    2. Floral expression of a gene encoding an E2-related ubiquitin-conjugating protein from Arabidopsis thaliana. Watts FZ, et al. Plant Mol Biol, 1994 Oct. PMID 7948890
    3. Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence. Wang S, et al. Int J Mol Sci, 2022 Sep 22. PMID 36232444, Free PMC Article
    4. Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Kraft E, et al. Plant Physiol, 2005 Dec. PMID 16339806, Free PMC Article
    5. Protein degradation in signaling. Callis J, et al. Curr Opin Plant Biol, 2000 Oct. PMID 11019805

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. UBC6, a ubiquitin-conjugating enzyme, participates in secondary cell wall thickening in the inflorescence stem of Arabidopsis.
      Title: UBC6, a ubiquitin-conjugating enzyme, participates in secondary cell wall thickening in the inflorescence stem of Arabidopsis.
    2. Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence.
      Title: Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337170.1
    NM_001337171.1
    NM_001337173.1
    NM_130166.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme 6
    NP_001318433.1
    • ubiquitin-conjugating enzyme 6 (UBC6); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608), Ubiquitin-conjugating enzyme (InterPro:IPR015581); BEST Arabidopsis thaliana protein match is: ubiquitin-conjugating enzyme 5 (TAIR:AT1G63800.1); Has 8701 Blast hits to 8700 proteins in 389 species: Archae - 0; Bacteria - 2; Metazoa - 3940; Fungi - 1759; Plants - 1590; Viruses - 20; Other Eukaryotes - 1390 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18932019..18934138 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337172.1 → NP_001324871.1  ubiquitin-conjugating enzyme 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W0M8, A0A1P8B1E8

    2. NM_001337170.1 → NP_001318433.1  ubiquitin-conjugating enzyme 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49739, O82365, P42750, Q4TZ03
      UniProtKB/TrEMBL
      A0A178W274, A0A5S9X7M5
      Conserved Domains (1) summary
      pfam00179
      Location:7 → 143
      UQ_con; Ubiquitin-conjugating enzyme

    3. NM_001337171.1 → NP_001324870.1  ubiquitin-conjugating enzyme 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W274, A0A1P8B1K4

    4. NM_130166.4 → NP_566062.1  ubiquitin-conjugating enzyme 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566062.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49739, O82365, P42750, Q4TZ03
      UniProtKB/TrEMBL
      A0A178W274, A0A5S9X7M5
      Conserved Domains (1) summary
      pfam00179
      Location:7 → 143
      UQ_con; Ubiquitin-conjugating enzyme

    5. NM_001337173.1 → NP_001324869.1  ubiquitin-conjugating enzyme 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W274, A0A1P8B1K4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    AAB32508.1
    P42750.2

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