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    INH3 inhibitor-3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817688, updated on 18-Sep-2024

    Summary

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    Official Symbol
    INH3
    Official Full Name
    inhibitor-3
    Primary source
    TAIR:AT2G31305
    Locus tag
    AT2G31305
    See related
    Araport:AT2G31305
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    INHIBITOR-3
    Summary
    Encodes inhibitor-3 (Inh3), a regulatory subunit of protein phosphatase 1 (PP1). Inh3 inhibits the phosphatase activity of the PP1 catalytic subunit (PP1c). Biochemical analyses demonstrate that Inh3 binds to PP1c via the RVxF motif of Inh3, a consensus PP1c-binding sequence both in vitro and in vivo.
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    Genomic context

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    See INH3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (13350369..13351490)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene transcription factor bHLH155-like protein Neighboring gene Ubiquitin carboxyl-terminal hydrolase family protein Neighboring gene actin-related protein C1B Neighboring gene ncRNA Neighboring gene LOB domain-containing protein 14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and functional characterization of inhibitor-3, a regulatory subunit of protein phosphatase 1 in plants. Takemiya A, et al. Plant Physiol, 2009 May. PMID 19329567, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_128687.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    part_of protein phosphatase type 1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inhibitor-3
    NP_565720.1
    • INHIBITOR-3 (INH3); CONTAINS InterPro DOMAIN/s: Protein phosphatase inhibitor (InterPro:IPR011107); Has 380 Blast hits to 378 proteins in 162 species: Archae - 0; Bacteria - 0; Metazoa - 171; Fungi - 140; Plants - 35; Viruses - 0; Other Eukaryotes - 34 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13350369..13351490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128687.2 → NP_565720.1  inhibitor-3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565720.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8S8F7
      UniProtKB/TrEMBL
      A0A178VZ39, A0A5S9WUL3, A0A5S9X2V0
      Conserved Domains (1) summary
      pfam07491
      Location:31 → 70
      PPI_Ypi1; Protein phosphatase inhibitor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8S8F7.1

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