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    RFNR2 root FNR 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839930, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RFNR2
    Official Full Name
    root FNR 2
    Primary source
    TAIR:AT1G30510
    Locus tag
    AT1G30510
    See related
    Araport:AT1G30510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRFNR2; F26G16.13; F26G16_13; FERREDOXIN:NADP(H) OXIDOREDUCTASE; root FNR 2
    Summary
    Encodes a root-type ferredoxin:NADP(H) oxidoreductase.
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    Genomic context

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    See RFNR2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (10806930..10809188, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene nuclear factor Y, subunit A7 Neighboring gene GATA zinc finger protein Neighboring gene acyl-activating enzyme 14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis Root-Type Ferredoxin:NADP(H) Oxidoreductase 2 is Involved in Detoxification of Nitrite in Roots. Hachiya T, et al. Plant Cell Physiol, 2016 Nov. PMID 27615794
    2. Root-type ferredoxin-NADP(+) oxidoreductase isoforms in Arabidopsis thaliana: Expression patterns, location and stress responses. Grabsztunowicz M, et al. Plant Cell Environ, 2021 Feb. PMID 33131061
    3. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Root-type ferredoxin-NADP(+) oxidoreductase isoforms in Arabidopsis thaliana: Expression patterns, location and stress responses.
      Title: Root-type ferredoxin-NADP(+) oxidoreductase isoforms in Arabidopsis thaliana: Expression patterns, location and stress responses.
    2. RFNR2 has a major role in reduction of toxic nitrite in roots.
      Title: Arabidopsis Root-Type Ferredoxin:NADP(H) Oxidoreductase 2 is Involved in Detoxification of Nitrite in Roots.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_102787.1
    NM_179403.4
    NM_202213.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper ion binding HDA PubMed 
    enables ferredoxin-NADP+ reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    root FNR 2
    NP_564355.1
    • root FNR 2 (RFNR2); FUNCTIONS IN: oxidoreductase activity, copper ion binding; INVOLVED IN: oxidation reduction; LOCATED IN: chloroplast, thylakoid membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Oxidoreductase FAD/NAD(P)-binding (InterPro:IPR001433), Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Ferredoxin Reductase (InterPro:IPR015701), Flavoprotein pyridine nucleotide cytochrome reductase (InterPro:IPR001709), Ferredoxin--NADP reductase (InterPro:IPR012146); BEST Arabidopsis thaliana protein match is: root FNR 1 (TAIR:AT4G05390.1); Has 6645 Blast hits to 6645 proteins in 1680 species: Archae - 12; Bacteria - 3566; Metazoa - 779; Fungi - 733; Plants - 567; Viruses - 0; Other Eukaryotes - 988 (source: NCBI BLink).
    NP_849734.1
    • root FNR 2 (RFNR2); FUNCTIONS IN: oxidoreductase activity, copper ion binding; INVOLVED IN: oxidation reduction; LOCATED IN: chloroplast, thylakoid membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Oxidoreductase FAD/NAD(P)-binding (InterPro:IPR001433), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Ferredoxin Reductase (InterPro:IPR015701), Flavoprotein pyridine nucleotide cytochrome reductase (InterPro:IPR001709), Ferredoxin--NADP reductase (InterPro:IPR012146); BEST Arabidopsis thaliana protein match is: root FNR 1 (TAIR:AT4G05390.1); Has 6670 Blast hits to 6670 proteins in 1686 species: Archae - 12; Bacteria - 3590; Metazoa - 780; Fungi - 733; Plants - 567; Viruses - 0; Other Eukaryotes - 988 (source: NCBI BLink).
    NP_973942.1
    • root FNR 2 (RFNR2); FUNCTIONS IN: oxidoreductase activity, copper ion binding; INVOLVED IN: oxidation reduction; LOCATED IN: thylakoid membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ferredoxin reductase-type FAD-binding domain (InterPro:IPR017927), Oxidoreductase, FAD-binding domain (InterPro:IPR008333), Ferredoxin--NADP reductase (InterPro:IPR012146), Oxidoreductase FAD/NAD(P)-binding (InterPro:IPR001433), Riboflavin synthase-like beta-barrel (InterPro:IPR017938), Ferredoxin Reductase (InterPro:IPR015701), Flavoprotein pyridine nucleotide cytochrome reductase (InterPro:IPR001709); BEST Arabidopsis thaliana protein match is: root FNR 1 (TAIR:AT4G05390.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      10806930..10809188 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179403.4 → NP_849734.1  root FNR 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849734.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3ED46, Q3ED47, Q8LA56, Q9S9P8
      UniProtKB/TrEMBL
      A0A178WKQ0, A0A5S9WEC9
      Conserved Domains (1) summary
      PLN03116
      Location:76 → 382
      PLN03116; ferredoxin--NADP+ reductase; Provisional

    2. NM_102787.1 → NP_564355.1  root FNR 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564355.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WMZ1
      Conserved Domains (2) summary
      cd06208
      Location:91 → 381
      CYPOR_like_FNR; These ferredoxin reductases are related to the NADPH cytochrome p450 reductases (CYPOR), but lack the FAD-binding region connecting sub-domain. Ferredoxin-NADP+ reductase (FNR) is an FAD-containing enzyme that catalyzes the reversible electron transfer ...
      PLN03116
      Location:75 → 381
      PLN03116; ferredoxin--NADP+ reductase; Provisional

    3. NM_202213.1 → NP_973942.1  root FNR 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973942.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WMZ1
      Conserved Domains (2) summary
      cd06208
      Location:27 → 317
      CYPOR_like_FNR; These ferredoxin reductases are related to the NADPH cytochrome p450 reductases (CYPOR), but lack the FAD-binding region connecting sub-domain. Ferredoxin-NADP+ reductase (FNR) is an FAD-containing enzyme that catalyzes the reversible electron transfer ...
      PLN03116
      Location:11 → 317
      PLN03116; ferredoxin--NADP+ reductase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9S9P8.1

    Gene LinkOut

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