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    PDE247 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837083, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PDE247
    Official Full Name
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    TAIR:AT1G05750
    Locus tag
    AT1G05750
    See related
    Araport:AT1G05750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CLB19; pigment defective 247; T20M3.1; T20M3_1
    Summary
    Encodes a pentatricopeptide repeat protein required for editing of rpoA and clpP chloroplast transcripts.
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    Genomic context

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    See PDE247 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (1721509..1724734)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene FAM136A-like protein (DUF842) Neighboring gene ncRNA Neighboring gene FAM136A-like protein (DUF842) Neighboring gene Mannose-binding lectin superfamily protein Neighboring gene Mannose-binding lectin superfamily protein Neighboring gene Vacuolar ATPase assembly integral membrane protein VMA21-like domain-containing protein Neighboring gene microRNA ath-MIR5656 precursor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CLB19, a pentatricopeptide repeat protein required for editing of rpoA and clpP chloroplast transcripts. Chateigner-Boutin AL, et al. Plant J, 2008 Nov. PMID 18657233
    2. Predictable alteration of sequence recognition by RNA editing factors from Arabidopsis. Kindgren P, et al. Plant Cell, 2015 Feb. PMID 25649437, Free PMC Article
    3. Two interacting PPR proteins are major Arabidopsis editing factors in plastid and mitochondria. Guillaumot D, et al. Proc Natl Acad Sci U S A, 2017 Aug 15. PMID 28760958, Free PMC Article
    4. Functional analysis of the Arabidopsis thaliana CHLOROPLAST BIOGENESIS 19 pentatricopeptide repeat editing protein. Ramos-Vega M, et al. New Phytol, 2015 Oct. PMID 25980341
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. these analyses provide important clues about the particularities of the CLB19 editing protein.
      Title: Functional analysis of the Arabidopsis thaliana CHLOROPLAST BIOGENESIS 19 pentatricopeptide repeat editing protein.
    2. By altering S motifs in CLB19 and another editing factor, OTP82,the specificity of these factors in vivo, can be altered.
      Title: Predictable alteration of sequence recognition by RNA editing factors from Arabidopsis.
    3. CLB19 (PDE247) is essential for chloroplast development, and is required for the correct RNA editing of the chloroplast clpP and rpoA transcripts.
      Title: CLB19, a pentatricopeptide repeat protein required for editing of rpoA and clpP chloroplast transcripts.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001331574.1
    NM_100455.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_172066.3
    • pigment defective 247 (PDE247); CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: mitochondrial editing factor 21 (TAIR:AT2G20540.1); Has 41993 Blast hits to 13871 proteins in 254 species: Archae - 1; Bacteria - 18; Metazoa - 75; Fungi - 77; Plants - 41230; Viruses - 0; Other Eukaryotes - 592 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1721509..1724734
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100455.3 → NP_172066.3  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172066.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MA50
      UniProtKB/TrEMBL
      A0A178W105
      Conserved Domains (2) summary
      PLN03077
      Location:37 → 488
      PLN03077; Protein ECB2; Provisional
      sd00004
      Location:274 → 301
      PPR; PPR repeat [structural motif]

    2. NM_001331574.1 → NP_001322717.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9MA50
      UniProtKB/TrEMBL
      A0A178W105
      Conserved Domains (2) summary
      PLN03077
      Location:37 → 488
      PLN03077; Protein ECB2; Provisional
      sd00004
      Location:274 → 301
      PPR; PPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MA50.1

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