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    CKX5 cytokinin oxidase 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843881, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CKX5
    Official Full Name
    cytokinin oxidase 5
    Primary source
    TAIR:AT1G75450
    Locus tag
    AT1G75450
    See related
    Araport:AT1G75450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CYTOKININ OXIDASE 5; ATCKX5; ATCKX6; cytokinin oxidase 5; CYTOKININ OXIDASE 6; F1B16.2; F1B16_2
    Summary
    This gene used to be called AtCKX6. It encodes a protein whose sequence is similar to cytokinin oxidase/dehydrogenase, which catalyzes the degradation of cytokinins.
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    Genomic context

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    See CKX5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (28314458..28318375, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene BEL1-like homeodomain 11 Neighboring gene ncRNA Neighboring gene ubiquitin-conjugating enzyme 16 Neighboring gene ncRNA Neighboring gene ATP-dependent protease La (LON) domain protein Neighboring gene purine permease

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytokinin oxidase gene CKX5 is modulated in the immunity of Arabidopsis to Botrytis cinerea. Wang R, et al. PLoS One, 2024. PMID 38478518, Free PMC Article
    2. Cytokinin regulates the activity of reproductive meristems, flower organ size, ovule formation, and thus seed yield in Arabidopsis thaliana. Bartrina I, et al. Plant Cell, 2011 Jan. PMID 21224426, Free PMC Article
    3. Structure and function of cytokinin oxidase/dehydrogenase genes of maize, rice, Arabidopsis and other species. Schmülling T, et al. J Plant Res, 2003 Jun. PMID 12721786
    4. Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity. Werner T, et al. Plant Cell, 2003 Nov. PMID 14555694, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Cytokinin oxidase gene CKX5 is modulated in the immunity of Arabidopsis to Botrytis cinerea.
      Title: Cytokinin oxidase gene CKX5 is modulated in the immunity of Arabidopsis to Botrytis cinerea.
    2. ckx3 ckx5 mutants form more silques and seeds, and regulate the activity of the reproductive meristems.
      Title: Cytokinin regulates the activity of reproductive meristems, flower organ size, ovule formation, and thus seed yield in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    NM_001198473.1
    NM_106199.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytokinin dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cytokinin dehydrogenase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cytokinin catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in cytokinin metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular region TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytokinin oxidase 5
    NP_001185402.1
    • cytokinin oxidase 5 (CKX5); CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), Oxygen oxidoreductase covalent FAD-binding site (InterPro:IPR006093), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase/dehydrogenase 1 (TAIR:AT2G41510.1).
    NP_177678.2
    • cytokinin oxidase 5 (CKX5); CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), Oxygen oxidoreductase covalent FAD-binding site (InterPro:IPR006093), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase/dehydrogenase 1 (TAIR:AT2G41510.1); Has 6615 Blast hits to 6610 proteins in 1194 species: Archae - 154; Bacteria - 4290; Metazoa - 145; Fungi - 1218; Plants - 369; Viruses - 0; Other Eukaryotes - 439 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      28314458..28318375 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106199.5 → NP_177678.2  cytokinin oxidase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177678.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q67YU0, Q9FUJ0, Q9FWT3
      UniProtKB/TrEMBL
      A0A5S9WUL0, A0A654EP91
      Conserved Domains (1) summary
      PLN02441
      Location:1 → 522
      PLN02441; cytokinin dehydrogenase

    2. NM_001198473.1 → NP_001185402.1  cytokinin oxidase 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185402.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2E944, F4HZ40
      Conserved Domains (3) summary
      PLN02441
      Location:1 → 519
      PLN02441; cytokinin dehydrogenase
      pfam01565
      Location:63 → 207
      FAD_binding_4; FAD binding domain
      pfam09265
      Location:239 → 517
      Cytokin-bind; Cytokinin dehydrogenase 1, FAD and cytokinin binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q67YU0.1

    Gene LinkOut

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