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    Golph3l golgi phosphoprotein 3-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310669, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Golph3lprovided by RGD
    Official Full Name
    golgi phosphoprotein 3-likeprovided by RGD
    Primary source
    RGD:1359281
    See related
    EnsemblRapid:ENSRNOG00000047620 AllianceGenome:RGD:1359281
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable cargo adaptor activity and phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in several processes, including Golgi vesicle transport; positive regulation of protein secretion; and protein targeting to Golgi apparatus. Predicted to be located in Golgi apparatus. Predicted to be active in Golgi cisterna; cytosol; and trans-Golgi network. Orthologous to human GOLPH3L (golgi phosphoprotein 3 like). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 104.9), Thymus (RPKM 103.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Golph3l in Genome Data Viewer
    Location:
    2q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (185840879..185872037)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (183151941..183183094)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (197720259..197749060)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene cathepsin S Neighboring gene HORMA domain containing 1 Neighboring gene transfer RNA leucine (anticodon AAG) 16 Neighboring gene RNA, U6 small nuclear 857 Neighboring gene endosulfine alpha Neighboring gene MCL1 apoptosis regulator, BCL2 family member

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. GOLPH3L antagonizes GOLPH3 to determine Golgi morphology. Ng MM, et al. Mol Biol Cell, 2013 Mar. PMID 23345592, Free PMC Article
    2. Proteomics characterization of abundant Golgi membrane proteins. Bell AW, et al. J Biol Chem, 2001 Feb 16. PMID 11042173
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC94181

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cargo adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cargo adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables phosphatidylinositol-4-phosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in Golgi organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in Golgi organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi vesicle budding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of protein secretion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of protein secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein targeting to Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein targeting to Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi cisterna ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in trans-Golgi network ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Golgi phosphoprotein 3-like
    Names
    GPP34-related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007698.1 → NP_001007699.1  Golgi phosphoprotein 3-like

      See identical proteins and their annotated locations for NP_001007699.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081987
      UniProtKB/Swiss-Prot
      Q66H74
      UniProtKB/TrEMBL
      A0A0G2K9Q1, A6K300
      Related
      ENSRNOP00000064938.1, ENSRNOT00000070919.4
      Conserved Domains (1) summary
      pfam05719
      Location:48 → 259
      GPP34; Golgi phosphoprotein 3 (GPP34)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      185840879..185872037
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039102357.2 → XP_038958285.1  Golgi phosphoprotein 3-like isoform X1

      UniProtKB/TrEMBL
      A0A0G2K9Q1
      Related
      ENSRNOP00000106584.1, ENSRNOT00000165904.1
      Conserved Domains (1) summary
      pfam05719
      Location:56 → 267
      GPP34; Golgi phosphoprotein 3 (GPP34)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66H74.1 GenPept UniProtKB/Swiss-Prot:Q66H74

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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