NCED4 nine-cis-epoxycarotenoid dioxygenase 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NCED4
Official Full Name: nine-cis-epoxycarotenoid dioxygenase 4
Primary source: TAIR:AT4G19170
Locus tag: AT4G19170
See related: Araport:AT4G19170
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: carotenoid cleavage dioxygenase 4; CCD4; nine-cis-epoxycarotenoid dioxygenase 4; T18B16.140; T18B16_140
Summary: chloroplast-targeted member of a family of enzymes similar to nine-cis-epoxycarotenoid dioxygenase
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Genomic context

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See NCED4 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 1

Sequence:: Chromosome: 4; NC_003075.7 (10481619..10483879)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

enzymatic potential to form acyclic regulatory metabolites
Title: Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites.
CCD4 plays a major role in beta-carotene degradation in drying seeds and senescing leaves
Title: Carotenoid cleavage dioxygenase4 is a negative regulator of β-carotene content in Arabidopsis seeds.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_118036.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in beta-carotene catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in cytosol	HDA more info	PubMed
located_in plastoglobule	HDA more info	PubMed

General protein information

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Preferred Names: nine-cis-epoxycarotenoid dioxygenase 4

NP_193652.1

nine-cis-epoxycarotenoid dioxygenase 4 (NCED4); LOCATED IN: chloroplast, plastoglobule; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Carotenoid oxygenase (InterPro:IPR004294); BEST Arabidopsis thaliana protein match is: nine-cis-epoxycarotenoid dioxygenase 5 (TAIR:AT1G30100.1); Has 2918 Blast hits to 2864 proteins in 491 species: Archae - 16; Bacteria - 796; Metazoa - 323; Fungi - 173; Plants - 887; Viruses - 0; Other Eukaryotes - 723 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

10481619..10483879

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_118036.3 → NP_193652.1 nine-cis-epoxycarotenoid dioxygenase 4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_193652.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O49675

UniProtKB/TrEMBL

A0A7G2EYQ3

Conserved Domains (1) summary

cl10080
Location:17 → 594

RPE65; Retinal pigment epithelial membrane protein