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    Ypel4 yippee-like 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 502643, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ypel4provided by RGD
    Official Full Name
    yippee-like 4provided by RGD
    Primary source
    RGD:1560142
    See related
    EnsemblRapid:ENSRNOG00000069900 AllianceGenome:RGD:1560142
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable metal ion binding activity. Predicted to act upstream of or within several processes, including negative regulation of erythrocyte clearance; negative regulation of erythrocyte differentiation; and protein localization to plasma membrane. Predicted to be located in nucleolus. Orthologous to human YPEL4 (yippee like 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 184.9), Brain (RPKM 82.1) and 6 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ypel4 in Genome Data Viewer
    Location:
    3q24
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (90222060..90227395)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (69815373..69820708)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (72134719..72139204)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 19 Neighboring gene zinc finger DHHC-type palmitoyltransferase 5 Neighboring gene uncharacterized LOC120101590 Neighboring gene cleavage factor polyribonucleotide kinase subunit 1 Neighboring gene microRNA 130a Neighboring gene microRNA 3590 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of erythrocyte clearance ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within negative regulation of erythrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of cell shape ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein yippee-like 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024369.1 → NP_001019540.1  protein yippee-like 4

      See identical proteins and their annotated locations for NP_001019540.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083749
      UniProtKB/Swiss-Prot
      Q5XID5
      UniProtKB/TrEMBL
      A0A8I6A1T5, A6HMR2
      Related
      ENSRNOP00000085506.1, ENSRNOT00000095945.2
      Conserved Domains (1) summary
      cl13152
      Location:28 → 118
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      90222060..90227395
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039105727.2 → XP_038961655.1  protein yippee-like 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XID5
      UniProtKB/TrEMBL
      A0A8I6A1T5, A6HMR2
      Conserved Domains (1) summary
      cl13152
      Location:28 → 118
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    2. XM_063284405.1 → XP_063140475.1  protein yippee-like 4 isoform X1

      UniProtKB/Swiss-Prot
      Q5XID5
      UniProtKB/TrEMBL
      A0A8I6A1T5, A6HMR2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XID5.1 GenPept UniProtKB/Swiss-Prot:Q5XID5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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