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    Lin52 lin-52 DREAM MuvB core complex component [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362763, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lin52provided by RGD
    Official Full Name
    lin-52 DREAM MuvB core complex componentprovided by RGD
    Primary source
    RGD:1306798
    See related
    EnsemblRapid:ENSRNOG00000043441 AllianceGenome:RGD:1306798
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306798
    Summary
    Predicted to be involved in regulation of DNA-templated transcription. Predicted to be part of DRM complex. Orthologous to human LIN52 (lin-52 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 72.2), Brain (RPKM 68.6) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Lin52 in Genome Data Viewer
    Location:
    6q31
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (109829896..109927122)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (104098818..104199323)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (108167412..108264459)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene basal body orientation factor 1 Neighboring gene ring finger protein 113A2 Neighboring gene aldehyde dehydrogenase 6 family, member A1 Neighboring gene visual system homeobox 2 Neighboring gene ATP binding cassette subfamily D member 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of DRM complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein lin-52 homolog
    Names
    lin-52 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398854.1NP_001385783.1  protein lin-52 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      Related
      ENSRNOP00000105493.1, ENSRNOT00000166526.1
    2. NM_001398855.1NP_001385784.1  protein lin-52 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      Related
      ENSRNOP00000061629.3, ENSRNOT00000064426.5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      109829896..109927122
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006240356.5XP_006240418.1  protein lin-52 homolog isoform X1

      See identical proteins and their annotated locations for XP_006240418.1

      Conserved Domains (1) summary
      pfam10044
      Location:18100
      LIN52; Retinal tissue protein
    2. XM_063262122.1XP_063118192.1  protein lin-52 homolog isoform X8

    3. XM_017594487.3XP_017449976.1  protein lin-52 homolog isoform X2

      Related
      ENSRNOP00000104334.1, ENSRNOT00000133031.1
    4. XM_017594488.3XP_017449977.1  protein lin-52 homolog isoform X3

      Related
      ENSRNOP00000104915.1, ENSRNOT00000161805.1
    5. XM_008764889.4XP_008763111.1  protein lin-52 homolog isoform X5

      See identical proteins and their annotated locations for XP_008763111.1

      Related
      ENSRNOP00000112655.1, ENSRNOT00000151317.1
      Conserved Domains (1) summary
      pfam10044
      Location:18100
      LIN52; Retinal tissue protein
    6. XM_006240358.5XP_006240420.1  protein lin-52 homolog isoform X4

      See identical proteins and their annotated locations for XP_006240420.1

      UniProtKB/TrEMBL
      A0A8I6GAV2
      Related
      ENSRNOP00000084676.2, ENSRNOT00000104563.2
      Conserved Domains (1) summary
      pfam10044
      Location:18118
      LIN52; Retinal tissue protein
    7. XM_008764890.4XP_008763112.1  protein lin-52 homolog isoform X6

      See identical proteins and their annotated locations for XP_008763112.1

      Conserved Domains (1) summary
      pfam10044
      Location:1898
      LIN52; Retinal tissue protein
    8. XM_063262121.1XP_063118191.1  protein lin-52 homolog isoform X7

    RNA

    1. XR_354978.5 RNA Sequence

    2. XR_001838493.3 RNA Sequence

    3. XR_010052121.1 RNA Sequence