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    Mterf4 mitochondrial transcription termination factor 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363289, updated on 9-Dec-2024

    Summary

    Official Symbol
    Mterf4provided by RGD
    Official Full Name
    mitochondrial transcription termination factor 4provided by RGD
    Primary source
    RGD:1562440
    See related
    EnsemblRapid:ENSRNOG00000037376 AllianceGenome:RGD:1562440
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Mterfd2
    Summary
    Predicted to enable rRNA binding activity. Predicted to be involved in mitochondrial ribosome assembly and mitochondrial transcription. Predicted to act upstream of or within several processes, including camera-type eye development; protein targeting to mitochondrion; and ribosome assembly. Predicted to be located in cytosol. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MTERF4 (mitochondrial transcription termination factor 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 83.3), Kidney (RPKM 82.4) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mterf4 in Genome Data Viewer
    Location:
    9q36
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (101281560..101286236, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (93834162..93838838, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (100440482..100445158, complement)

    Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene ciliary rootlet coiled-coil, rootletin family member 2 Neighboring gene uncharacterized LOC134480612 Neighboring gene sushi, nidogen and EGF-like domains 1 Neighboring gene ubiquitin-associated domain-containing protein 1 pseudogene Neighboring gene PAS domain containing serine/threonine kinase Neighboring gene protein NYNRIN-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC112635

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables rRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within camera-type eye development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within heart development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial ribosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within mitochondrial transcription ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within protein targeting to mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within ribosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    transcription termination factor 4, mitochondrial
    Names
    MTERF domain containing 2
    mTERF domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037209.2NP_001032286.1  transcription termination factor 4, mitochondrial

      See identical proteins and their annotated locations for NP_001032286.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000009
      UniProtKB/Swiss-Prot
      Q4G078
      UniProtKB/TrEMBL
      A6JQY2
      Related
      ENSRNOP00000053397.2, ENSRNOT00000056558.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086027.1 Reference GRCr8

      Range
      101281560..101286236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)