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    Hid1 HID1 domain containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287822, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Hid1provided by RGD
    Official Full Name
    HID1 domain containingprovided by RGD
    Primary source
    RGD:1311422
    See related
    EnsemblRapid:ENSRNOG00000003464 AllianceGenome:RGD:1311422
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1311422
    Summary
    Predicted to be located in cytoplasmic microtubule; cytoplasmic side of Golgi membrane; and cytosol. Predicted to be active in Golgi medial cisterna; Golgi trans cisterna; and membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 105. Orthologous to human HID1 (HID1 domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 154.5), Lung (RPKM 88.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Hid1 in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (101088526..101109011, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (100589555..100610050, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (103899160..103919649, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene otopetrin 2 Neighboring gene otopetrin 3 Neighboring gene uncharacterized LOC134480902 Neighboring gene cerebellar degeneration-related protein 2-like Neighboring gene mitochondrial ribosomal protein L58

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. HID-1 is a peripheral membrane protein primarily associated with the medial- and trans- Golgi apparatus. Wang L, et al. Protein Cell, 2011 Jan. PMID 21337012, Free PMC Article
    2. MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis. Fong KW, et al. J Cell Sci, 2013 Feb 1. PMID 23264731, Free PMC Article
    3. In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Principe S, et al. Proteomics, 2013 May. PMID 23533145, Free PMC Article
    4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi medial cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi medial cisterna ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi trans cisterna IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi trans cisterna ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic side of Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    protein HID1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001304290.1 → NP_001291219.1  protein HID1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      D4A0C3
      Conserved Domains (1) summary
      pfam12722
      Location:1 → 784
      Hid1; High-temperature-induced dauer-formation protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      101088526..101109011 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268780.1 → XP_063124850.1  protein HID1 isoform X3

    2. XM_039085671.2 → XP_038941599.1  protein HID1 isoform X2

      Conserved Domains (1) summary
      pfam12722
      Location:1 → 746
      Hid1; High-temperature-induced dauer-formation protein

    3. XM_006247774.5 → XP_006247836.1  protein HID1 isoform X1

      See identical proteins and their annotated locations for XP_006247836.1

      Related
      ENSRNOP00000004718.6, ENSRNOT00000004718.8
      Conserved Domains (1) summary
      pfam12722
      Location:1 → 785
      Hid1; High-temperature-induced dauer-formation protein
    Nucleotide Protein Strain
    Heading Accession and Version

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