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    AL1 alfin-like 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830444, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AL1
    Official Full Name
    alfin-like 1
    Primary source
    TAIR:AT5G05610
    Locus tag
    AT5G05610
    See related
    Araport:AT5G05610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    alfin-like 1; MOP10.15; MOP10_15
    Summary
    Encodes a member of the Alfin1-like family of nuclear-localized PHD (plant homeodomain) domain containing proteins. All AL proteins except AL3 bind to di- or trimethylated histone H3 (H3K4me3/2). Members of this family include: AT5G05610 (AL1), AT3G11200 (AL2), AT3G42790 (AL3), AT5G26210 (AL4), AT5G20510 (AL5), AT2G02470 (AL6), AT1G14510 (AL7).
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    Genomic context

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    See AL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (1676889..1679107, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene gamma-tubulin complex protein 2 Neighboring gene Amino acid permease family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes. Molitor AM, et al. PLoS Genet, 2014 Jan. PMID 24465219, Free PMC Article
    2. Arabidopsis ING and Alfin1-like protein families localize to the nucleus and bind to H3K4me3/2 via plant homeodomain fingers. Lee WY, et al. Plant J, 2009 May. PMID 19154204
    3. Enhanced Y1H assays for Arabidopsis. Gaudinier A, et al. Nat Methods, 2011 Oct 30. PMID 22037706, Free PMC Article
    4. Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation. de Lucas M, et al. Plant Cell, 2016 Oct. PMID 27650334, Free PMC Article
    5. Promoter-based integration in plant defense regulation. Li B, et al. Plant Physiol, 2014 Dec. PMID 25352272, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120643.2
    NM_180444.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methylated histone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    alfin-like 1
    NP_196180.1
    • alfin-like 1 (AL1); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Protein of unknown function DUF3594 (InterPro:IPR021998), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: alfin-like 2 (TAIR:AT3G11200.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
    NP_850775.1
    • alfin-like 1 (AL1); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Protein of unknown function DUF3594 (InterPro:IPR021998), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: alfin-like 2 (TAIR:AT3G11200.1); Has 1460 Blast hits to 1420 proteins in 178 species: Archae - 0; Bacteria - 0; Metazoa - 679; Fungi - 238; Plants - 468; Viruses - 0; Other Eukaryotes - 75 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1676889..1679107 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180444.3 → NP_850775.1  alfin-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850775.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FFF5
      UniProtKB/TrEMBL
      A0A178UPZ2, A0A5S9Y201
      Conserved Domains (2) summary
      cd15613
      Location:187 → 237
      PHD_AL_plant; PHD finger found in plant Alfin1-like (AL) proteins
      pfam12165
      Location:11 → 136
      Alfin

    2. NM_120643.2 → NP_196180.1  alfin-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196180.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FFF5
      UniProtKB/TrEMBL
      A0A178UPZ2, A0A5S9Y201
      Conserved Domains (2) summary
      cd15613
      Location:187 → 237
      PHD_AL_plant; PHD finger found in plant Alfin1-like (AL) proteins
      pfam12165
      Location:11 → 136
      Alfin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FFF5.1

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