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    GSL12 glucan synthase-like 12 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831140, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GSL12
    Official Full Name
    glucan synthase-like 12
    Primary source
    TAIR:AT5G13000
    Locus tag
    AT5G13000
    See related
    Araport:AT5G13000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGSL12; callose synthase 3; CALS3; glucan synthase-like 12; gsl12; T24H18.170; T24H18_170
    Summary
    encodes a gene similar to callose synthase
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    Genomic context

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    See GSL12 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    44
    Sequence:
    Chromosome: 5; NC_003076.8 (4110171..4121489, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Calcium-dependent lipid-binding (CaLB domain) plant phosphoribosyltransferase family protein Neighboring gene Cell differentiation, Rcd1-like protein Neighboring gene CLAVATA3/ESR-RELATED 40 Neighboring gene RNA helicase family protein Neighboring gene Emsy N Terminus (ENT)/ plant Tudor-like domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Localization of Arabidopsis Glucan Synthase-Like 5, 8, and 12 to plasmodesmata and the GSL8-dependent role of PDLP5 in regulating plasmodesmal permeability. Saatian B, et al. Plant Signal Behav, 2023 Dec 31. PMID 36645916, Free PMC Article
    2. Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Nühse TS, et al. Mol Cell Proteomics, 2003 Nov. PMID 14506206
    3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_001161240.2
    NM_121303.8

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 1,3-beta-D-glucan synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 1,3-beta-D-glucan synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in (1->3)-beta-D-glucan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 1,3-beta-D-glucan synthase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane HDA PubMed 
    located_in plasmodesma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glucan synthase-like 12
    NP_001154712.2
    • glucan synthase-like 12 (GSL12); FUNCTIONS IN: transferase activity, transferring glycosyl groups, 1,3-beta-glucan synthase activity; INVOLVED IN: 1,3-beta-glucan biosynthetic process; LOCATED IN: 1,3-beta-glucan synthase complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 48 (InterPro:IPR003440), Protein of unknown function DUF605 (InterPro:IPR006745); BEST Arabidopsis thaliana protein match is: callose synthase 1 (TAIR:AT1G05570.1); Has 1373 Blast hits to 1031 proteins in 173 species: Archae - 0; Bacteria - 0; Metazoa - 71; Fungi - 677; Plants - 549; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink).
    NP_196804.6
    • glucan synthase-like 12 (GSL12); FUNCTIONS IN: transferase activity, transferring glycosyl groups, 1,3-beta-glucan synthase activity; INVOLVED IN: 1,3-beta-glucan biosynthetic process; LOCATED IN: 1,3-beta-glucan synthase complex, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 48 (InterPro:IPR003440), Protein of unknown function DUF605 (InterPro:IPR006745); BEST Arabidopsis thaliana protein match is: callose synthase 1 (TAIR:AT1G05570.1); Has 1374 Blast hits to 1031 proteins in 173 species: Archae - 0; Bacteria - 0; Metazoa - 71; Fungi - 677; Plants - 550; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4110171..4121489 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121303.8 → NP_196804.6  glucan synthase-like 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196804.6

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4K2E8, Q9LXT9
      UniProtKB/TrEMBL
      A0A5S9Y413, A0A654G0Z6
      Conserved Domains (3) summary
      pfam02364
      Location:1057 → 1814
      Glucan_synthase; 1,3-beta-glucan synthase component
      pfam04652
      Location:50 → 177
      Vta1; Vta1 like
      pfam14288
      Location:321 → 434
      FKS1_dom1; 1,3-beta-glucan synthase subunit FKS1, domain-1

    2. NM_001161240.2 → NP_001154712.2  glucan synthase-like 12 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154712.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G0Z6, F4K116
      Conserved Domains (3) summary
      pfam02364
      Location:1057 → 1780
      Glucan_synthase; 1,3-beta-glucan synthase component
      pfam04652
      Location:50 → 177
      Vta1; Vta1 like
      pfam14288
      Location:322 → 434
      FKS1_dom1; 1,3-beta-glucan synthase subunit FKS1, domain-1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LXT9.3

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