ITPK1 Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ITPK1
Official Full Name: Inositol 1,3,4-trisphosphate 5/6-kinase family protein
Primary source: TAIR:AT5G16760
Locus tag: AT5G16760
See related: Araport:AT5G16760
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 3; 4) P3 5/6-kinase 1; 4-TRISPHOSPHATE 5/6-KINASE; Arabidopsis thaliana inositol (1; AtITPK1; inositol (1; INOSITOL 1
Summary: Encodes a inositol 1,3,4-trisphosphate 5/6-kinase.
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Genomic context

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See ITPK1 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 1

Sequence:: Chromosome: 5; NC_003076.8 (5509625..5511322)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ITPK1 Regulates Jasmonate-Controlled Root Development in Arabidopsis thaliana.
Title: ITPK1 Regulates Jasmonate-Controlled Root Development in Arabidopsis thaliana.
INOSITOL (1,3,4) TRIPHOSPHATE 5/6 KINASE1-dependent inositol polyphosphates regulate auxin responses in Arabidopsis.
Title: INOSITOL (1,3,4) TRIPHOSPHATE 5/6 KINASE1-dependent inositol polyphosphates regulate auxin responses in Arabidopsis.
Arabidopsis inositol polyphosphate kinases IPK1 and ITPK1 modulate crosstalk between SA-dependent immunity and phosphate-starvation responses.
Title: Arabidopsis inositol polyphosphate kinases IPK1 and ITPK1 modulate crosstalk between SA-dependent immunity and phosphate-starvation responses.
An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels.
Title: An ATP-responsive metabolic cassette comprised of inositol tris/tetrakisphosphate kinase 1 (ITPK1) and inositol pentakisphosphate 2-kinase (IPK1) buffers diphosphosphoinositol phosphate levels.
ITPK1 protein phosphorylates phytic acid to yield inositol heptakisphosphate.
Title: Arabidopsis ITPK1 and ITPK2 Have an Evolutionarily Conserved Phytic Acid Kinase Activity.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_121682.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables inositol-1,3,4-trisphosphate 5-kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables inositol-1,3,4-trisphosphate 6-kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables inositol-3,4,5,6-tetrakisphosphate 1-kinase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables signaling receptor binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in auxin-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in inositol trisphosphate metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in inositol trisphosphate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within myo-inositol hexakisphosphate biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IPI Inferred from Physical Interaction more info	PubMed

General protein information

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Preferred Names: Inositol 1,3,4-trisphosphate 5/6-kinase family protein

NP_197178.1

Inositol 1,3,4-trisphosphate 5/6-kinase family protein; FUNCTIONS IN: inositol or phosphatidylinositol kinase activity, catalytic activity; INVOLVED IN: inositol and derivative phosphorylation; LOCATED IN: intracellular; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Inositol-tetrakisphosphate 1-kinase (InterPro:IPR017427), ATP-grasp fold (InterPro:IPR011761), Inositol 1, 3, 4-trisphosphate 56-kinase (InterPro:IPR008656); BEST Arabidopsis thaliana protein match is: Inositol 1,3,4-trisphosphate 5/6-kinase family protein (TAIR:AT4G08170.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

5509625..5511322

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_121682.3 → NP_197178.1 Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_197178.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O81633, Q9SBA5

UniProtKB/TrEMBL

A0A178U6K3, A0A5S9Y5B1

Conserved Domains (1) summary

PLN02941
Location:2 → 316

PLN02941; inositol-tetrakisphosphate 1-kinase