NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_007372.2 RefSeqGene
- Range
-
5002..41361
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_000213.5 → NP_000204.3 integrin beta-4 isoform 1 precursor
See identical proteins and their annotated locations for NP_000204.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AC087749, AI318403, CA391583, X51841, X52186, X53587
- Consensus CDS
-
CCDS11727.1
- UniProtKB/Swiss-Prot
- A0AVL6, O14690, O14691, O15339, O15340, O15341, P16144, Q0VF97, Q9UIQ4
- UniProtKB/TrEMBL
-
B7ZLD8
- Related
- ENSP00000200181.3, ENST00000200181.8
- Conserved Domains (6) summary
-
- cd00063
Location:1220 → 1313
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1529 → 1611
- fn3; Fibronectin type III domain
- pfam00362
Location:37 → 453
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:990 → 1084
- Calx-beta; Calx-beta domain
- pfam07965
Location:626 → 709
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:543 → 573
- EGF_2; EGF-like domain
-
NM_001005619.1 → NP_001005619.1 integrin beta-4 isoform 2 precursor
See identical proteins and their annotated locations for NP_001005619.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame exon in one place but has an additional in-frame exon in another place, as compared to variant 1. The encoded isoform 2 thus differs in two regions, as compared to isoform 1.
- Source sequence(s)
-
AI318403, X51841, X52186, X53587
- Consensus CDS
-
CCDS32736.1
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1220 → 1313
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1512 → 1594
- fn3; Fibronectin type III domain
- pfam00362
Location:37 → 453
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:990 → 1084
- Calx-beta; Calx-beta domain
- pfam07965
Location:626 → 709
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:543 → 573
- EGF_2; EGF-like domain
-
NM_001005731.3 → NP_001005731.1 integrin beta-4 isoform 3 precursor
See identical proteins and their annotated locations for NP_001005731.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, as compared to variant 1. The encoded isoform 3 thus lacks an internal segment, as compared to isoform 1.
- Source sequence(s)
-
AI318403, CA391583, X51841, X52186, X53587
- Consensus CDS
-
CCDS58599.1
- UniProtKB/TrEMBL
-
B7ZLD8
- Related
- ENSP00000405536.3, ENST00000450894.7
- Conserved Domains (6) summary
-
- cd00063
Location:1220 → 1313
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1459 → 1541
- fn3; Fibronectin type III domain
- pfam00362
Location:37 → 453
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:990 → 1084
- Calx-beta; Calx-beta domain
- pfam07965
Location:626 → 709
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:543 → 573
- EGF_2; EGF-like domain
-
NM_001321123.2 → NP_001308052.1 integrin beta-4 isoform 3 precursor
Status: REVIEWED
- Source sequence(s)
-
BC143742, CA391583, X51841, X52186
- Consensus CDS
-
CCDS58599.1
- UniProtKB/TrEMBL
-
B7ZLD8
- Related
- ENSP00000463651.1, ENST00000579662.5
- Conserved Domains (6) summary
-
- cd00063
Location:1220 → 1313
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1459 → 1541
- fn3; Fibronectin type III domain
- pfam00362
Location:37 → 453
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:990 → 1084
- Calx-beta; Calx-beta domain
- pfam07965
Location:626 → 709
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:543 → 573
- EGF_2; EGF-like domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000017.11 Reference GRCh38.p14 Primary Assembly
- Range
-
75721459..75757818
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005257311.5 → XP_005257368.1 integrin beta-4 isoform X2
See identical proteins and their annotated locations for XP_005257368.1
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1220 → 1313
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1582 → 1664
- fn3; Fibronectin type III domain
- pfam00362
Location:37 → 453
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:990 → 1084
- Calx-beta; Calx-beta domain
- pfam07965
Location:626 → 709
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:543 → 573
- EGF_2; EGF-like domain
-
XM_047435927.1 → XP_047291883.1 integrin beta-4 isoform X7
- UniProtKB/TrEMBL
-
B7ZLD8
- Related
- ENSP00000400217.2, ENST00000449880.7
-
XM_047435929.1 → XP_047291885.1 integrin beta-4 isoform X10
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_005257309.3 → XP_005257366.1 integrin beta-4 isoform X2
See identical proteins and their annotated locations for XP_005257366.1
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1220 → 1313
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1582 → 1664
- fn3; Fibronectin type III domain
- pfam00362
Location:37 → 453
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:990 → 1084
- Calx-beta; Calx-beta domain
- pfam07965
Location:626 → 709
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:543 → 573
- EGF_2; EGF-like domain
-
XM_047435926.1 → XP_047291882.1 integrin beta-4 isoform X3
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_006721866.4 → XP_006721929.1 integrin beta-4 isoform X1
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1255 → 1348
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1617 → 1699
- fn3; Fibronectin type III domain
- pfam00362
Location:72 → 488
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:1025 → 1119
- Calx-beta; Calx-beta domain
- pfam07965
Location:661 → 744
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:578 → 608
- EGF_2; EGF-like domain
-
XM_006721867.4 → XP_006721930.1 integrin beta-4 isoform X4
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1255 → 1348
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1564 → 1646
- fn3; Fibronectin type III domain
- pfam00362
Location:72 → 488
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:1025 → 1119
- Calx-beta; Calx-beta domain
- pfam07965
Location:661 → 744
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:578 → 608
- EGF_2; EGF-like domain
-
XM_011524751.3 → XP_011523053.1 integrin beta-4 isoform X6
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1255 → 1348
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1627 → 1712
- fn3; Fibronectin type III domain
- pfam00362
Location:72 → 488
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:1025 → 1119
- Calx-beta; Calx-beta domain
- pfam07965
Location:661 → 744
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:578 → 608
- EGF_2; EGF-like domain
-
XM_006721868.4 → XP_006721931.1 integrin beta-4 isoform X5
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1255 → 1348
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1547 → 1629
- fn3; Fibronectin type III domain
- pfam00362
Location:72 → 488
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:1025 → 1119
- Calx-beta; Calx-beta domain
- pfam07965
Location:661 → 744
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:578 → 608
- EGF_2; EGF-like domain
-
XM_006721870.4 → XP_006721933.1 integrin beta-4 isoform X8
- UniProtKB/TrEMBL
-
B7ZLD8
- Conserved Domains (6) summary
-
- cd00063
Location:1255 → 1348
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:1494 → 1576
- fn3; Fibronectin type III domain
- pfam00362
Location:72 → 488
- Integrin_beta; Integrin, beta chain
- pfam03160
Location:1025 → 1119
- Calx-beta; Calx-beta domain
- pfam07965
Location:661 → 744
- Integrin_B_tail; Integrin beta tail domain
- pfam07974
Location:578 → 608
- EGF_2; EGF-like domain
-
XM_047435928.1 → XP_047291884.1 integrin beta-4 isoform X9
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_011524752.3 → XP_011523054.1 integrin beta-4 isoform X11
- Conserved Domains (3) summary
-
- cd00063
Location:535 → 628
- FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
- pfam00041
Location:897 → 979
- fn3; Fibronectin type III domain
- pfam03160
Location:305 → 399
- Calx-beta; Calx-beta domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060941.1 Alternate T2T-CHM13v2.0
- Range
-
76614671..76651043
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054315967.1 → XP_054171942.1 integrin beta-4 isoform X2
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315973.1 → XP_054171948.1 integrin beta-4 isoform X7
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315976.1 → XP_054171951.1 integrin beta-4 isoform X10
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315968.1 → XP_054171943.1 integrin beta-4 isoform X2
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315974.1 → XP_054171949.1 integrin beta-4 isoform X8
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315969.1 → XP_054171944.1 integrin beta-4 isoform X3
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315966.1 → XP_054171941.1 integrin beta-4 isoform X1
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315972.1 → XP_054171947.1 integrin beta-4 isoform X6
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315970.1 → XP_054171945.1 integrin beta-4 isoform X4
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315971.1 → XP_054171946.1 integrin beta-4 isoform X5
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315975.1 → XP_054171950.1 integrin beta-4 isoform X9
- UniProtKB/TrEMBL
-
B7ZLD8
-
XM_054315977.1 → XP_054171952.1 integrin beta-4 isoform X11