Gpr27 G protein-coupled receptor 27 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gpr27provided by RGD
Official Full Name: G protein-coupled receptor 27provided by RGD
Primary source: RGD:71067
See related: EnsemblRapid:ENSRNOG00000010880 AllianceGenome:RGD:71067
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Sreb1
Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within positive regulation of insulin secretion involved in cellular response to glucose stimulus and positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human GPR27 (G protein-coupled receptor 27). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 4q34

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (133884894..133886027)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (132328364..132329497)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (132137793..132138926)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The Activation of GPR27 Increases Cytosolic L-Lactate in 3T3 Embryonic Cells and Astrocytes.
Title: The Activation of GPR27 Increases Cytosolic L-Lactate in 3T3 Embryonic Cells and Astrocytes.

Submit: New GeneRIF Correction

General gene information

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Markers

D4Rat57 (e-PCR)
- UniSTS:118851

UniSTS:493241 (e-PCR)
- UniSTS:493241

UniSTS:487638 (e-PCR)
- UniSTS:487638

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of insulin secretion involved in cellular response to glucose stimulus	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: probable G-protein coupled receptor 27

Names: super conserved receptor expressed in brain 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.