Stard4 StAR-related lipid transfer domain containing 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Stard4provided by RGD
Official Full Name: StAR-related lipid transfer domain containing 4provided by RGD
Primary source: RGD:1309475
See related: EnsemblRapid:ENSRNOG00000020468 AllianceGenome:RGD:1309475
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to be involved in cholesterol transport and positive regulation of steroid metabolic process. Predicted to be located in cytoplasmic vesicle. Predicted to be active in cytosol and endoplasmic reticulum. Orthologous to human STARD4 (StAR related lipid transfer domain containing 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Liver (RPKM 143.5), Thymus (RPKM 118.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 18p12

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	18	NC_086036.1 (25088831..25104172, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	18	NC_051353.1 (24814683..24830024, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	18	NC_005117.4 (25982210..25997555, complement)

Chromosome 18 - NC_086036.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables cholesterol binding	IBA Inferred from Biological aspect of Ancestor more info
enables cholesterol binding	ISO Inferred from Sequence Orthology more info
enables cholesterol transfer activity	IBA Inferred from Biological aspect of Ancestor more info
enables cholesterol transfer activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cholesterol import	IBA Inferred from Biological aspect of Ancestor more info
involved_in cholesterol import	ISO Inferred from Sequence Orthology more info
involved_in cholesterol transport involved in cholesterol storage	IBA Inferred from Biological aspect of Ancestor more info
involved_in cholesterol transport involved in cholesterol storage	ISO Inferred from Sequence Orthology more info
involved_in intracellular cholesterol transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular cholesterol transport	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of bile acid biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of cholesterol metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoplasmic vesicle	ISO Inferred from Sequence Orthology more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: stAR-related lipid transfer protein 4

Names: StAR-related lipid transfer (START) domain containing 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.