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    Zmym3 zinc finger MYM-type containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317260, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zmym3provided by RGD
    Official Full Name
    zinc finger MYM-type containing 3provided by RGD
    Primary source
    RGD:1564967
    See related
    EnsemblRapid:ENSRNOG00000003707 AllianceGenome:RGD:1564967
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in cytoskeleton organization and regulation of cell morphogenesis. Predicted to be located in nucleoplasm. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human ZMYM3 (zinc finger MYM-type containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 147.7), Adrenal (RPKM 113.2) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zmym3 in Genome Data Viewer
    Location:
    Xq22
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (70568573..70584221, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (66528585..66544234, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (71298737..71313529, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene neuroligin 3 Neighboring gene gap junction protein, beta 1 Neighboring gene non-POU domain containing, octamer-binding Neighboring gene small nucleolar RNA SNORA4 Neighboring gene integrin subunit beta 1 binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC112818, MGC156821

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zinc finger MYM-type protein 3
    Names
    zinc finger, MYM-type 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040155.2NP_001035245.2  zinc finger MYM-type protein 3

      See identical proteins and their annotated locations for NP_001035245.2

      Status: PROVISIONAL

      Source sequence(s)
      CH473966
      UniProtKB/TrEMBL
      A0A8I6A895, A6IQB8, E9PTE5
      Related
      ENSRNOP00000088523.1, ENSRNOT00000076004.4
      Conserved Domains (3) summary
      smart00746
      Location:314350
      TRASH; metallochaperone-like domain
      pfam06467
      Location:674713
      zf-FCS; MYM-type Zinc finger with FCS sequence motif
      pfam12012
      Location:11871353
      DUF3504; Domain of unknown function (DUF3504)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      70568573..70584221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001037785.1: Suppressed sequence

      Description
      NM_001037785.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.