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    CG30268 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37610, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG30268provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050268
    Locus tag
    Dmel_CG30268
    See related
    AllianceGenome:FB:FBgn0050268
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13520; Dmel\CG30268
    Summary
    Predicted to be involved in sperm flagellum assembly. Predicted to be active in sperm flagellum. Is expressed in spermatogonium. Human ortholog(s) of this gene implicated in spermatogenic failure 84. Orthologous to human CFAP61 (cilia and flagella associated protein 61). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30268 in Genome Data Viewer
    Location:
    59A3-59A3; 2-101 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22712701..22717247)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18600206..18604752)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43735 Neighboring gene uncharacterized protein Neighboring gene Odorant-binding protein 58d Neighboring gene jitterbug Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila Vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation. Korolchuk VI, et al. J Cell Sci, 2007 Dec 15. PMID 18057029
    2. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    3. Affinity Density: a novel genomic approach to the identification of transcription factor regulatory targets. Hazelett DJ, et al. Bioinformatics, 2009 Jul 1. PMID 19401399, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in sperm flagellum assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30268-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22712701..22717247
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137868.2 → NP_611712.2  uncharacterized protein Dmel_CG30268 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611712.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W206
      Conserved Domains (2) summary
      pfam07992
      Location:793 → 1017
      Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
      pfam16092
      Location:14 → 286
      DUF4821; Domain of unknown function (DUF4821)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W206 Q9W206

    Gene LinkOut

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