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    Tstd2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 272027, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tstd2provided by MGI
    Official Full Name
    thiosulfate sulfurtransferase (rhodanese)-like domain containing 2provided by MGI
    Primary source
    MGI:MGI:3039624
    See related
    Ensembl:ENSMUSG00000035495 AllianceGenome:MGI:3039624
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    3010020C06
    Summary
    Orthologous to human TSTD2 (thiosulfate sulfurtransferase like domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in heart adult (RPKM 15.4), genital fat pad adult (RPKM 9.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tstd2 in Genome Data Viewer
    Location:
    4 B1; 4 24.49 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (46114746..46138725, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (46114746..46138725, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene tropomodulin 1 Neighboring gene predicted gene, 52729 Neighboring gene STARR-seq mESC enhancer starr_10118 Neighboring gene predicted gene, 54220 Neighboring gene nuclear cap binding protein subunit 1 Neighboring gene STARR-seq mESC enhancer starr_10120 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:46209123-46209232 Neighboring gene xeroderma pigmentosum, complementation group A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    2. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
    3. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
    4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2
    Names
    likely ortholog of H. sapiens chromosome 9 open reading frame 97 (C9orf97)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355375.1 → NP_001342304.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AA914127, AK028258, BP760190, BY013797, CD549731, CO427336
      Consensus CDS
      CCDS38757.1
      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Related
      ENSMUSP00000103399.2, ENSMUST00000107770.2
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    2. NM_001355376.1 → NP_001342305.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AA914127, AK028258, BP760190, CD549731, CJ049260, CJ063145, CO427336
      Consensus CDS
      CCDS38757.1
      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    3. NM_173033.3 → NP_766621.3  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

      See identical proteins and their annotated locations for NP_766621.3

      Status: VALIDATED

      Source sequence(s)
      AK028258, AL732615, BY013797, CD549731
      Consensus CDS
      CCDS38757.1
      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Related
      ENSMUSP00000103401.2, ENSMUST00000107772.8
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      46114746..46138725 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164172.1 → XP_036020065.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X2

      Conserved Domains (1) summary
      cl00125
      Location:7 → 234
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    2. XM_006537960.4 → XP_006538023.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006538023.1

      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    3. XM_006537963.5 → XP_006538026.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006538026.1

      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    4. XM_006537962.5 → XP_006538025.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006538025.1

      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    5. XM_006537961.5 → XP_006538024.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006538024.1

      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    6. XM_036164171.1 → XP_036020064.1  thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      B1AWH0, Q3U269, Q6PES9, Q8C1D7
      Conserved Domains (1) summary
      cl00125
      Location:169 → 459
      RHOD; Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...

    RNA

    1. XR_004941915.1 RNA Sequence

    2. XR_001784151.3 RNA Sequence

    3. XR_003954957.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3U269.3 GenPept UniProtKB/Swiss-Prot:Q3U269

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