AY074887 cDNA sequence AY074887 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: AY074887provided by MGI
Official Full Name: cDNA sequence AY074887provided by MGI
Primary source: MGI:MGI:3575512
See related: Ensembl:ENSMUSG00000044820 AllianceGenome:MGI:3575512
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mcpr1
Summary: Acts upstream of or within apoptotic signaling pathway; negative regulation of stem cell proliferation; and regulation of G1/S transition of mitotic cell cycle. Located in cytoplasm and extracellular space. Is expressed in several structures, including heart; liver; lung; spleen; and upper jaw. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

Location:: 9 B; 9 29.84 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	9	NC_000075.7 (54857528..54858238, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	9	NC_000075.6 (54950244..54950954, complement)

Chromosome 9 - NC_000075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MCPR1 protein gene related to mouse cleft palate was cloned and found its ORF encode a 132 amino acid residue polypeptides.
Title: Cloning of full-length cDNA sequence of a novel candidate gene related to mouse cleft palate.
Mcpr1 functions as one of retinoic acid up-regulated genes inducing cleft palate by regulating proliferation and apoptosis of embryonic palatal mesenchymal cells
Title: Identification and characterization of a novel gene, Mcpr1, and its possible function in the proliferation of embryonic palatal mesenchymal cells.

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General gene information

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Markers

NoName (e-PCR)
- UniSTS:492304

AY074887 (e-PCR), detects polymorphism
- UniSTS:516121

D10Mit157.2 (e-PCR), detects polymorphism
- UniSTS:126061

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within apoptotic signaling pathway	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of cell population proliferation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within negative regulation of stem cell proliferation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of G1/S transition of mitotic cell cycle	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of stem cell proliferation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in extracellular space	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: cleft palate-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.