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    PAPS2 poly(A) polymerase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817127, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAPS2
    Official Full Name
    poly(A) polymerase 2
    Primary source
    TAIR:AT2G25850
    Locus tag
    AT2G25850
    See related
    Araport:AT2G25850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F17H15.12; F17H15_12; poly(A) polymerase 2
    Summary
    Encodes a poly(A) polymerase. Located in the nucleus.
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    Genomic context

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    See PAPS2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (11025345..11030808, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene YebC-like protein Neighboring gene Nucleotidylyl transferase superfamily protein Neighboring gene haloacid dehalogenase-like hydrolase family protein Neighboring gene ataurora2 Neighboring gene Oleosin family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An interaction between an Arabidopsis poly(A) polymerase and a homologue of the 100 kDa subunit of CPSF. Elliott BJ, et al. Plant Mol Biol, 2003 Feb. PMID 12602868
    2. Characterization of genes encoding poly(A) polymerases in plants: evidence for duplication and functional specialization. Meeks LR, et al. PLoS One, 2009 Nov 26. PMID 19956626, Free PMC Article
    3. Novel alternative splicing of mRNAs encoding poly(A) polymerases in Arabidopsis. Addepalli B, et al. Biochim Biophys Acta, 2004 Aug 12. PMID 15297145
    4. The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis. Xu R, et al. Plant Mol Biol, 2006 Jul. PMID 16897494
    5. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. Hunt AG, et al. BMC Genomics, 2008 May 14. PMID 18479511, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036340.1
    NM_001202674.2
    NM_001336022.1
    NM_001336023.1
    NM_001336024.1
    NM_001336025.1
    NM_001336026.1
    NM_128145.4
    NM_179740.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables poly(A) RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    poly(A) polymerase 2
    NP_001031417.1
    • poly(A) polymerase 2 (PAPS2); CONTAINS InterPro DOMAIN/s: Poly(A) polymerase (InterPro:IPR014492), Nucleotidyltransferase, class I, C-terminal-like (InterPro:IPR011068), Poly(A) polymerase, central domain (InterPro:IPR007012), Nucleotidyl transferase domain (InterPro:IPR002934), Poly(A) polymerase, RNA-binding domain (InterPro:IPR007010); BEST Arabidopsis thaliana protein match is: nuclear poly(a) polymerase (TAIR:AT4G32850.6); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001189603.1
    • poly(A) polymerase 2 (PAPS2); CONTAINS InterPro DOMAIN/s: Poly(A) polymerase (InterPro:IPR014492), Poly(A) polymerase, central domain (InterPro:IPR007012), Nucleotidyltransferase, class I, C-terminal-like (InterPro:IPR011068), Nucleotidyl transferase domain (InterPro:IPR002934), Poly(A) polymerase, RNA-binding domain (InterPro:IPR007010); BEST Arabidopsis thaliana protein match is: nuclear poly(a) polymerase (TAIR:AT4G32850.9).
    NP_565611.1
    • poly(A) polymerase 2 (PAPS2); CONTAINS InterPro DOMAIN/s: Poly(A) polymerase (InterPro:IPR014492), Nucleotidyltransferase, class I, C-terminal-like (InterPro:IPR011068), Poly(A) polymerase, central domain (InterPro:IPR007012), Nucleotidyl transferase domain (InterPro:IPR002934), Poly(A) polymerase, RNA-binding domain (InterPro:IPR007010); BEST Arabidopsis thaliana protein match is: nuclear poly(a) polymerase (TAIR:AT4G32850.10); Has 815 Blast hits to 807 proteins in 221 species: Archae - 0; Bacteria - 15; Metazoa - 260; Fungi - 213; Plants - 191; Viruses - 0; Other Eukaryotes - 136 (source: NCBI BLink).
    NP_850071.1
    • poly(A) polymerase 2 (PAPS2); CONTAINS InterPro DOMAIN/s: Poly(A) polymerase (InterPro:IPR014492), Nucleotidyltransferase, class I, C-terminal-like (InterPro:IPR011068), Poly(A) polymerase, central domain (InterPro:IPR007012), Nucleotidyl transferase domain (InterPro:IPR002934), Poly(A) polymerase, RNA-binding domain (InterPro:IPR007010); BEST Arabidopsis thaliana protein match is: nuclear poly(a) polymerase (TAIR:AT4G32850.6); Has 814 Blast hits to 806 proteins in 220 species: Archae - 0; Bacteria - 13; Metazoa - 260; Fungi - 214; Plants - 191; Viruses - 0; Other Eukaryotes - 136 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11025345..11030808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179740.2 → NP_850071.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850071.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EW70
      Conserved Domains (2) summary
      pfam04926
      Location:371 → 502
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:24 → 367
      PAP_central; Poly(A) polymerase central domain

    2. NM_128145.4 → NP_565611.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565611.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4ISP7, F4ISP8, F4ISP9, O82312, Q94BP6, Q9LKX0
      UniProtKB/TrEMBL
      A0A178VXR1, A0A654EW70
      Conserved Domains (2) summary
      pfam04926
      Location:371 → 502
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:24 → 367
      PAP_central; Poly(A) polymerase central domain

    3. NM_001336024.1 → NP_001324472.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VW48, A0A1P8B067, A0A384L4S8, A0A654EW70

    4. NM_001336023.1 → NP_001324473.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VW48, A0A1P8B067, A0A384L4S8, A0A654EW70

    5. NM_001336022.1 → NP_001324471.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VW48, A0A1P8B067, A0A384L4S8, A0A654EW70

    6. NM_001202674.2 → NP_001189603.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189603.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EW70
      Conserved Domains (2) summary
      pfam04926
      Location:371 → 502
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:24 → 367
      PAP_central; Poly(A) polymerase central domain

    7. NM_001336025.1 → NP_001324470.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VW48, A0A1P8B067, A0A384L4S8, A0A654EW70

    8. NM_001336026.1 → NP_001324469.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B088, A0A654EW70

    9. NM_001036340.1 → NP_001031417.1  poly(A) polymerase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031417.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EW70
      Conserved Domains (2) summary
      pfam04926
      Location:371 → 502
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:24 → 367
      PAP_central; Poly(A) polymerase central domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82312.2

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