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    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844262, updated on 18-Sep-2024

    Summary

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    Official Full Name
    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
    Primary source
    TAIR:AT1G79210
    Locus tag
    AT1G79210
    See related
    Araport:AT1G79210
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    YUP8H12R.19; YUP8H12R_19
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (29796081..29798836, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene myb domain protein 63 Neighboring gene ARM repeat superfamily protein Neighboring gene splicing regulatory glutamine/lysine-rich-like protein Neighboring gene Mitochondrial transcription termination factor family protein Neighboring gene mercaptopyruvate sulfurtransferase 1 Neighboring gene tRNA-Arg

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes. Book AJ, et al. J Biol Chem, 2010 Aug 13. PMID 20516081, Free PMC Article
    2. Proteomic analysis of the 26S proteasome reveals its direct interaction with transit peptides of plastid protein precursors for their degradation. Sako K, et al. J Proteome Res, 2014 Jul 3. PMID 24846764
    3. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article
    4. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084376.1
    NM_001084377.1
    NM_106572.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome core complex, alpha-subunit complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
    NP_001077845.1
    • N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein; FUNCTIONS IN: endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: defense response to bacterium, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, alpha-subunit, conserved site (InterPro:IPR000426), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: proteasome subunit PAB1 (TAIR:AT1G16470.2); Has 6788 Blast hits to 6787 proteins in 497 species: Archae - 889; Bacteria - 41; Metazoa - 2422; Fungi - 1564; Plants - 857; Viruses - 0; Other Eukaryotes - 1015 (source: NCBI BLink).
    NP_001077846.1
    • N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein; FUNCTIONS IN: endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: defense response to bacterium, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, alpha-subunit, conserved site (InterPro:IPR000426), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: proteasome subunit PAB1 (TAIR:AT1G16470.2); Has 6770 Blast hits to 6769 proteins in 496 species: Archae - 887; Bacteria - 41; Metazoa - 2415; Fungi - 1555; Plants - 857; Viruses - 0; Other Eukaryotes - 1015 (source: NCBI BLink).
    NP_178042.1
    • N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein; FUNCTIONS IN: endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: defense response to bacterium, ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, alpha-subunit, conserved site (InterPro:IPR000426), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: proteasome subunit PAB1 (TAIR:AT1G16470.2); Has 6770 Blast hits to 6769 proteins in 496 species: Archae - 887; Bacteria - 41; Metazoa - 2415; Fungi - 1555; Plants - 857; Viruses - 0; Other Eukaryotes - 1015 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29796081..29798836 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106572.6 → NP_178042.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178042.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64532, Q8L4A7
      UniProtKB/TrEMBL
      A0A178W2F8, A0A5S9WVQ5
      Conserved Domains (1) summary
      cd03750
      Location:6 → 232
      proteasome_alpha_type_2; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    2. NM_001084377.1 → NP_001077846.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077846.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64532, Q8L4A7
      UniProtKB/TrEMBL
      A0A178W2F8, A0A5S9WVQ5
      Conserved Domains (1) summary
      cd03750
      Location:6 → 232
      proteasome_alpha_type_2; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    3. NM_001084376.1 → NP_001077845.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077845.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O64532, Q8L4A7
      UniProtKB/TrEMBL
      A0A178W2F8, A0A5S9WVQ5
      Conserved Domains (1) summary
      cd03750
      Location:6 → 232
      proteasome_alpha_type_2; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L4A7.1

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