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    FUT4 fucosyltransferase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816031, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FUT4
    Official Full Name
    fucosyltransferase 4
    Primary source
    TAIR:AT2G15390
    Locus tag
    AT2G15390
    See related
    Araport:AT2G15390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    atfut4; F26H6.9; F26H6_9; fucosyltransferase 4
    Summary
    Predicted fucosyltransferase, based on similarity to FUT1, but not functionally redundant with FUT1.
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    Genomic context

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    See FUT4 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (6709116..6711156, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene fucosyltransferase 5 Neighboring gene pseudo Neighboring gene DNA-directed RNA polymerase family protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterisation of FUT4 and FUT6 α-(1 → 2)-fucosyltransferases reveals that absence of root arabinogalactan fucosylation increases Arabidopsis root growth salt sensitivity. Tryfona T, et al. PLoS One, 2014. PMID 24667545, Free PMC Article
    2. Biochemical and physiological characterization of fut4 and fut6 mutants defective in arabinogalactan-protein fucosylation in Arabidopsis. Liang Y, et al. J Exp Bot, 2013 Dec. PMID 24127514, Free PMC Article
    3. Functional identification of two nonredundant Arabidopsis alpha(1,2)fucosyltransferases specific to arabinogalactan proteins. Wu Y, et al. J Biol Chem, 2010 Apr 30. PMID 20194500, Free PMC Article
    4. Characterization of a family of Arabidopsis genes related to xyloglucan fucosyltransferase1. Sarria R, et al. Plant Physiol, 2001 Dec. PMID 11743104, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. characterisation of FUT4 and FUT6 alpha-(1 --> 2)-fucosyltransferases
      Title: Characterisation of FUT4 and FUT6 α-(1 → 2)-fucosyltransferases reveals that absence of root arabinogalactan fucosylation increases Arabidopsis root growth salt sensitivity.
    2. FUT4 was required for fucosylation of leaf arabinogalactan-proteins, while both FUT4 and FUT6 contributed to fucosylation of root arabinogalactan-proteins.
      Title: Biochemical and physiological characterization of fut4 and fut6 mutants defective in arabinogalactan-protein fucosylation in Arabidopsis.
    3. AtFUT4 and AtFUT6 are the first enzymes to be characterized for AGP glycosylation
      Title: Functional identification of two nonredundant Arabidopsis alpha(1,2)fucosyltransferases specific to arabinogalactan proteins.
    Submit: New GeneRIF Correction

    General gene information

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    NM_127099.3
    NM_201739.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alpha-(1,2)-fucosyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables fucosyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables fucosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables galactoside 2-alpha-L-fucosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell wall biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to salt stress IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    fucosyltransferase 4
    NP_179141.1
    • fucosyltransferase 4 (FUT4); FUNCTIONS IN: transferase activity, transferring glycosyl groups, fucosyltransferase activity; INVOLVED IN: cell wall biogenesis; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Xyloglucan fucosyltransferase (InterPro:IPR004938); BEST Arabidopsis thaliana protein match is: fucosyltransferase 5 (TAIR:AT2G15370.1); Has 339 Blast hits to 330 proteins in 19 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 332; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).
    NP_973468.2
    • fucosyltransferase 4 (FUT4); FUNCTIONS IN: transferase activity, transferring glycosyl groups, fucosyltransferase activity; INVOLVED IN: cell wall biogenesis; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Xyloglucan fucosyltransferase (InterPro:IPR004938); BEST Arabidopsis thaliana protein match is: fucosyltransferase 5 (TAIR:AT2G15370.1); Has 339 Blast hits to 330 proteins in 19 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 332; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6709116..6711156 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_201739.3 → NP_973468.2  fucosyltransferase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973468.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SJP2
      UniProtKB/TrEMBL
      W8Q3H6
      Conserved Domains (1) summary
      cl16914
      Location:50 → 504
      O-FucT_like; GDP-fucose protein O-fucosyltransferase and related proteins

    2. NM_127099.3 → NP_179141.1  fucosyltransferase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179141.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      W8Q3H6
      Conserved Domains (1) summary
      cl16914
      Location:22 → 472
      O-FucT_like; GDP-fucose protein O-fucosyltransferase and related proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJP2.2

    Gene LinkOut

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