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    TI1 trypsin inhibitor protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818952, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TI1
    Official Full Name
    trypsin inhibitor protein 1
    Primary source
    TAIR:AT2G43510
    Locus tag
    AT2G43510
    See related
    Araport:AT2G43510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATTI1; T1O24.25; TRYPSIN INHIBITOR; trypsin inhibitor protein 1
    Summary
    Member of the defensin-like (DEFL) family. Encodes putative trypsin inhibitor protein which may function in defense against herbivory.
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    Genomic context

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    See TI1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (18066960..18067860)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Plant regulator RWP-RK family protein Neighboring gene trypsin inhibitor protein 2 Neighboring gene scorpion toxin-like knottin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Population genetics of tandem trypsin inhibitor genes in Arabidopsis species with contrasting ecology and life history. Clauss MJ, et al. Mol Ecol, 2003 May. PMID 12694291
    2. Cuticular defects lead to full immunity to a major plant pathogen. Chassot C, et al. Plant J, 2007 Mar. PMID 17257167
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129912.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables sodium channel inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in secretory vesicle HDA PubMed 

    General protein information

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    Preferred Names
    trypsin inhibitor protein 1
    NP_181879.1
    • trypsin inhibitor protein 1 (TI1); FUNCTIONS IN: serine-type endopeptidase inhibitor activity; INVOLVED IN: defense response to fungus, defense response; LOCATED IN: endomembrane system, extracellular region; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Scorpion long chain toxin (InterPro:IPR002061), Knottin (InterPro:IPR003614); BEST Arabidopsis thaliana protein match is: Scorpion toxin-like knottin superfamily protein (TAIR:AT2G43535.1); Has 146 Blast hits to 146 proteins in 7 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 145; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18066960..18067860
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129912.4 → NP_181879.1  trypsin inhibitor protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181879.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22865, Q42328, Q6ZZP6
      UniProtKB/TrEMBL
      A0A178VRC4, A0A5S9X6P1, A0A654F1J2
      Conserved Domains (1) summary
      pfam00537
      Location:31 → 88
      Toxin_3; Scorpion toxin-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q42328.3

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