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    KTI1 kunitz trypsin inhibitor 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843660, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KTI1
    Official Full Name
    kunitz trypsin inhibitor 1
    Primary source
    TAIR:AT1G73260
    Locus tag
    AT1G73260
    See related
    Araport:AT1G73260
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA KUNITZ TRYPSIN INHIBITOR 1; ATKTI1; kunitz trypsin inhibitor 1; T18K17.7; T18K17_7
    Summary
    Encodes a trypsin inhibitor involved in modulating programmed cell death in plant-pathogen interactions.
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    Genomic context

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    See KTI1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (27547098..27548282, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nucleoporin protein Ndc1-Nup protein Neighboring gene GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase 1 Neighboring gene serine carboxypeptidase-like 6 Neighboring gene serine carboxypeptidase-like 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Kunitz trypsin inhibitor: an antagonist of cell death triggered by phytopathogens and fumonisin b1 in Arabidopsis. Li J, et al. Mol Plant, 2008 May. PMID 19825555
    2. Genome-wide expression profiling of the host response to root-knot nematode infection in Arabidopsis. Jammes F, et al. Plant J, 2005 Nov. PMID 16236154
    3. Arabidopsis Kunitz Trypsin Inhibitors in Defense Against Spider Mites. Arnaiz A, et al. Front Plant Sci, 2018. PMID 30042779, Free PMC Article
    4. Oviposition by pierid butterflies triggers defense responses in Arabidopsis. Little D, et al. Plant Physiol, 2007 Feb. PMID 17142483, Free PMC Article
    5. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_105985.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within programmed cell death IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to hydrogen peroxide IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to insect IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to molecule of bacterial origin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to molecule of fungal origin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to nematode IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salicylic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in secretory vesicle HDA PubMed 

    General protein information

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    Preferred Names
    kunitz trypsin inhibitor 1
    NP_565061.1
    • kunitz trypsin inhibitor 1 (KTI1); FUNCTIONS IN: endopeptidase inhibitor activity; INVOLVED IN: response to salt stress, response to hydrogen peroxide, defense response to bacterium, programmed cell death, response to salicylic acid stimulus; LOCATED IN: mitochondrion; EXPRESSED IN: 8 plant structures; EXPRESSED DURING: LP.06 six leaves visible, LP.04 four leaves visible, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Proteinase inhibitor I3, Kunitz legume (InterPro:IPR002160), Kunitz inhibitor ST1-like (InterPro:IPR011065); BEST Arabidopsis thaliana protein match is: Kunitz family trypsin and protease inhibitor protein (TAIR:AT1G17860.1); Has 626 Blast hits to 626 proteins in 98 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 625; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27547098..27548282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105985.3 → NP_565061.1  kunitz trypsin inhibitor 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565061.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8H190, Q8RXD5, Q93Y29, Q9CAT9
      UniProtKB/TrEMBL
      A0A178W827
      Conserved Domains (1) summary
      pfam00197
      Location:30 → 204
      Kunitz_legume; Trypsin and protease inhibitor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RXD5.1

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