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    RPL18 ribosomal protein L18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819725, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RPL18
    Official Full Name
    ribosomal protein L18
    Primary source
    TAIR:AT3G05590
    Locus tag
    AT3G05590
    See related
    Araport:AT3G05590
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CYTOPLASMIC RIBOSOMAL PROTEIN L18; F18C1.14; F18C1_14; ribosomal protein L18
    Summary
    Encodes cytoplasmic ribosomal protein L18.
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    Genomic context

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    See RPL18 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (1621355..1623052)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene dipeptide transport ATP-binding protein Neighboring gene Calcineurin-like metallo-phosphoesterase superfamily protein Neighboring gene ncRNA Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immunopurification of polyribosomal complexes of Arabidopsis for global analysis of gene expression. Zanetti ME, et al. Plant Physiol, 2005 Jun. PMID 15955926, Free PMC Article
    2. RPL18aB helps maintain suspensor identity during early embryogenesis. Xie F, et al. J Integr Plant Biol, 2018 Apr. PMID 29193792
    3. Ribosomal protein L18aB is required for both male gametophyte function and embryo development in Arabidopsis. Yan H, et al. Sci Rep, 2016 Aug 9. PMID 27502163, Free PMC Article
    4. Regulated nuclear trafficking of rpL10A mediated by NIK1 represents a defense strategy of plant cells against virus. Carvalho CM, et al. PLoS Pathog, 2008 Dec. PMID 19112492, Free PMC Article
    5. Arabidopsis DCP2, DCP1, and VARICOSE form a decapping complex required for postembryonic development. Xu J, et al. Plant Cell, 2006 Dec. PMID 17158604, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Suspensor-specific expression of RPL18aB could rescue the cell proliferation defects in rpl18aB suspensors.
      Title: RPL18aB helps maintain suspensor identity during early embryogenesis.
    2. The cell type-specific complementation of RPL18aB in rpl18aB was not able to recover the phenotype, indicating that RPL18aB may play an essential role in early cell fate determination. This work unravels a novel role in embryo development for a ribosomal protein, and provides insight into regulatory mechanism of early embryogenesis.
      Title: Ribosomal protein L18aB is required for both male gametophyte function and embryo development in Arabidopsis.
    3. The hes mutant role of the mitochondrial ribosomal L18 protein produced uncellularized endosperm and embryos arrested at the late globular stage. The mutant embryos differentiated partially on rescue medium with some forming callus.
      Title: Developmentally regulated HEART STOPPER, a mitochondrially targeted L18 ribosomal protein gene, is required for cell division, differentiation, and seed development in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337591.1
    NM_001337592.1
    NM_111432.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		  
    Process Evidence Code Pubs
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translation TAS
    Traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    NOT located_in Golgi apparatus RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in chloroplast HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    part_of cytosolic large ribosomal subunit HDA PubMed 
    part_of large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		  
    located_in plant-type vacuole HDA PubMed 
    located_in vacuole HDA PubMed 

    General protein information

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    Preferred Names
    ribosomal protein L18
    NP_187210.1
    • ribosomal protein L18 (RPL18); FUNCTIONS IN: structural constituent of ribosome; INVOLVED IN: translation; LOCATED IN: cytosolic large ribosomal subunit, plasma membrane, chloroplast, vacuole, large ribosomal subunit; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribosomal protein L18e/L15 (InterPro:IPR021131), Ribosomal protein L18e (InterPro:IPR000039); BEST Arabidopsis thaliana protein match is: Ribosomal protein L18e/L15 superfamily protein (TAIR:AT5G27850.1); Has 786 Blast hits to 785 proteins in 305 species: Archae - 30; Bacteria - 0; Metazoa - 334; Fungi - 154; Plants - 130; Viruses - 0; Other Eukaryotes - 138 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1621355..1623052
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111432.4 → NP_187210.1  ribosomal protein L18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187210.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42791, Q9M9W4
      UniProtKB/TrEMBL
      A0A178V8M9, A0A5S9X9D7, A0A654G4P0
      Conserved Domains (1) summary
      pfam17135
      Location:2 → 187
      Ribosomal_L18; Ribosomal protein 60S L18 and 50S L18e

    2. NM_001337591.1 → NP_001327673.1  ribosomal protein L18 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LT16

    3. NM_001337592.1 → NP_001327672.1  ribosomal protein L18 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LT16
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42791.2

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