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    LON3 lon protease 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819747, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LON3
    Official Full Name
    lon protease 3
    Primary source
    TAIR:AT3G05780
    Locus tag
    AT3G05780
    See related
    Araport:AT3G05780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10A16.7; F10A16_7; lon protease 3
    Summary
    Encodes a member of the Lon protease-like proteins (Lon1/At5g26860, Lon2/At5g47040, Lon3/At3g05780, Lon4/At3g05790). Lon is a multifunctional ATP-dependent protease which exists in bacteria, archaea and within organelles in eukaryotic cells. Lon proteases are responsible for the degradation of abnormal, damaged and unstable proteins.
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    Genomic context

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    See LON3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Sequence:
    Chromosome: 3; NC_003074.8 (1714941..1719608, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene lon protease-like protein Neighboring gene lon protease 4 Neighboring gene AtBS1(activation-tagged BRI1 suppressor 1)-interacting factor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    lon protease 3
    NP_566258.1
    • lon protease 3 (LON3); FUNCTIONS IN: in 6 functions; INVOLVED IN: proteolysis; LOCATED IN: mitochondrion; EXPRESSED IN: sperm cell; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), Peptidase S16, active site (InterPro:IPR008268), Peptidase S16, ATP-dependent protease La (InterPro:IPR004815), Peptidase S16, lon N-terminal (InterPro:IPR003111), Peptidase S16, Lon C-terminal (InterPro:IPR008269), ATPase, AAA+ type, core (InterPro:IPR003593), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Peptidase S16, Lon protease, C-terminal (InterPro:IPR001984); BEST Arabidopsis thaliana protein match is: lon protease 4 (TAIR:AT3G05790.1); Has 14658 Blast hits to 14489 proteins in 2407 species: Archae - 438; Bacteria - 7797; Metazoa - 399; Fungi - 597; Plants - 312; Viruses - 7; Other Eukaryotes - 5108 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1714941..1719608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111452.1 → NP_566258.1  lon protease 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566258.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M9L8
      UniProtKB/TrEMBL
      A0A5S9X9F8
      Conserved Domains (5) summary
      smart00464
      Location:111 → 164
      LON; Found in ATP-dependent protease La (LON)
      TIGR00763
      Location:114 → 920
      lon; endopeptidase La
      pfam00004
      Location:443 → 585
      AAA; ATPase family associated with various cellular activities (AAA)
      cl21455
      Location:399 → 466
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
      cl21678
      Location:716 → 920
      ChlI; Subunit ChlI of Mg-chelatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M9L8.1

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