ORTHL ORTHRUS-like protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ORTHL
Official Full Name: ORTHRUS-like protein
Primary source: TAIR:AT4G08590
Locus tag: AT4G08590
See related: Araport:AT4G08590
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 15935; ORL1; ORTH-LIKE 1; ORTHRUS-like; ORTHRUS-LIKE 1; T3F12.10; VARIANT IN METHYLATION 6; VIM6
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Genomic context

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See ORTHL in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 7

Sequence:: Chromosome: 4; NC_003075.7 (5463794..5466747, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001084888.1

Supported by ESTs:

NM_001340597.1

Supported by ESTs:

NM_001340598.1

Supported by ESTs:

NM_001340599.1

Supported by ESTs:

NM_001340600.1

Supported by ESTs:

NM_116928.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables histone binding	ISS Inferred from Sequence or Structural Similarity more info
enables methyl-CpG binding	ISS Inferred from Sequence or Structural Similarity more info
enables methyl-CpNpG binding	ISS Inferred from Sequence or Structural Similarity more info
enables methyl-CpNpN binding	ISS Inferred from Sequence or Structural Similarity more info
enables ubiquitin-protein transferase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein ubiquitination	IDA Inferred from Direct Assay more info	PubMed
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: ORTHRUS-like protein

NP_001078357.1

ORTHRUS-like (ORTHL); CONTAINS InterPro DOMAIN/s: SRA-YDG (InterPro:IPR003105), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: Zinc finger (C3HC4-type RING finger) family protein (TAIR:AT1G57820.1); Has 2781 Blast hits to 2709 proteins in 231 species: Archae - 0; Bacteria - 14; Metazoa - 1735; Fungi - 182; Plants - 616; Viruses - 10; Other Eukaryotes - 224 (source: NCBI BLink).

NP_192599.2

ORTHRUS-like (ORTHL); CONTAINS InterPro DOMAIN/s: SRA-YDG (InterPro:IPR003105), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: Zinc finger (C3HC4-type RING finger) family protein (TAIR:AT1G57820.2); Has 2775 Blast hits to 2701 proteins in 230 species: Archae - 0; Bacteria - 14; Metazoa - 1738; Fungi - 176; Plants - 609; Viruses - 10; Other Eukaryotes - 228 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

5463794..5466747 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_116928.4 → NP_192599.2 ORTHRUS-like protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_192599.2

Status: REVIEWED

UniProtKB/Swiss-Prot

O22280, O81463, Q500W6, Q681I0, Q709F3

UniProtKB/TrEMBL

A0A654FME8

Conserved Domains (3) summary

smart00466
Location:228 → 378

SRA; SET and RING finger associated domain

cd00162
Location:109 → 147

RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]

cl17238
Location:106 → 148

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
NM_001340597.1 → NP_001328494.1 ORTHRUS-like protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B4T9, A0A654FME8
NM_001340598.1 → NP_001328497.1 ORTHRUS-like protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B4U7

Conserved Domains (3) summary

smart00466
Location:228 → 362

SRA; SET and RING finger associated domain

cd00162
Location:109 → 147

RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]

cl17238
Location:106 → 148

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
NM_001340600.1 → NP_001328495.1 ORTHRUS-like protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B4V7, A0A654FME8
NM_001340599.1 → NP_001328496.1 ORTHRUS-like protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B4U7

Conserved Domains (3) summary

smart00466
Location:228 → 362

SRA; SET and RING finger associated domain

cd00162
Location:109 → 147

RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]

cl17238
Location:106 → 148

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
NM_001084888.1 → NP_001078357.1 ORTHRUS-like protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001078357.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A654FME8

Conserved Domains (2) summary

smart00466
Location:228 → 377

SRA; SET and RING finger associated domain

cd00162
Location:109 → 151

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...