RIBA3 monofunctional riboflavin biosynthesis protein RIBA 3 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: RIBA3
Official Full Name: monofunctional riboflavin biosynthesis protein RIBA 3
Primary source: TAIR:AT5G59750
Locus tag: AT5G59750
See related: Araport:AT5G59750
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtRIBA3; homolog of ribA 3; MTH12.13; MTH12_13
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See RIBA3 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 5

Sequence:: Chromosome: 5; NC_003076.8 (24073195..24075552)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_001203642.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables 3,4-dihydroxy-2-butanone-4-phosphate synthase activity	IEA Inferred from Electronic Annotation more info
enables GTP cyclohydrolase II activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in riboflavin biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info

General protein information

Go to the top of the page Help

Preferred Names: monofunctional riboflavin biosynthesis protein RIBA 3

NP_001190571.1

DHBP synthase RibB-like alpha/beta domain;GTP cyclohydrolase II; FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: GTP cyclohydrolase II (TAIR:AT5G64300.1).

NP_568913.1

DHBP synthase RibB-like alpha/beta domain;GTP cyclohydrolase II; FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: GTP cyclohydrolase II (TAIR:AT5G64300.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

24073195..24075552

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001345369.1 → NP_001332607.1 monofunctional riboflavin biosynthesis protein RIBA 3 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178UMK1, A0A1P8BHH7

Conserved Domains (1) summary

PLN02831
Location:67 → 441

PLN02831; Bifunctional GTP cyclohydrolase II/ 3,4-dihydroxy-2-butanone-4-phosphate synthase
NM_125367.6 → NP_568913.1 monofunctional riboflavin biosynthesis protein RIBA 3 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_568913.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9FN89

UniProtKB/TrEMBL

A0A178UKK3, A0A5S9YHW5, A0A654GDM9, A0A7G2FHI0

Conserved Domains (1) summary

PLN02831
Location:67 → 509

PLN02831; Bifunctional GTP cyclohydrolase II/ 3,4-dihydroxy-2-butanone-4-phosphate synthase
NM_001203642.1 → NP_001190571.1 monofunctional riboflavin biosynthesis protein RIBA 3 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001190571.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178UKK3, A0A7G2FHI0, F4KJA1

Conserved Domains (3) summary

PLN02831
Location:67 → 543

PLN02831; Bifunctional GTP cyclohydrolase II/ 3,4-dihydroxy-2-butanone-4-phosphate synthase

cd00641
Location:340 → 532

GTP_cyclohydro2; GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the ...

pfam00926
Location:104 → 333

DHBP_synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase