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    RANGAP2 RAN GTPase activating protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832052, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RANGAP2
    Official Full Name
    RAN GTPase activating protein 2
    Primary source
    TAIR:AT5G19320
    Locus tag
    AT5G19320
    See related
    Araport:AT5G19320
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    RAN GTPase activating protein 2
    Summary
    Encodes RAN GTPase activating protein 2. The protein is localized to the nuclear envelope during interphase.
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    Genomic context

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    See RANGAP2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (6505092..6507645, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene homeotic protein regulator Neighboring gene Defensin-like (DEFL) family protein Neighboring gene ARM repeat protein interacting with ABF2 Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant RanGAPs are localized at the nuclear envelope in interphase and associated with microtubules in mitotic cells. Pay A, et al. Plant J, 2002 Jun. PMID 12061901
    2. Two distinct interacting classes of nuclear envelope-associated coiled-coil proteins are required for the tissue-specific nuclear envelope targeting of Arabidopsis RanGAP. Zhao Q, et al. Plant Cell, 2008 Jun. PMID 18591351, Free PMC Article
    3. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    4. A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Jaquinod M, et al. Mol Cell Proteomics, 2007 Mar. PMID 17151019, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001343596.1
    NM_121937.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within nucleocytoplasmic transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    RAN GTPase activating protein 2
    NP_001318597.1
    • RAN GTPase activating protein 2 (RANGAP2); FUNCTIONS IN: RAN GTPase activator activity; INVOLVED IN: response to salt stress, nucleocytoplasmic transport; LOCATED IN: nuclear envelope, endoplasmic reticulum, plasma membrane, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: RAN GTPase activating protein 1 (TAIR:AT3G63130.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      6505092..6507645 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343596.1 → NP_001318597.1  RAN GTPase activating protein 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M651
      UniProtKB/TrEMBL
      A0A178UQD1, A0A5S9Y630
      Conserved Domains (3) summary
      sd00033
      Location:216 → 243
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13943
      Location:13 → 109
      WPP; WPP domain
      cl39015
      Location:183 → 450
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. NM_121937.5 → NP_197433.1  RAN GTPase activating protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197433.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M651
      UniProtKB/TrEMBL
      A0A178UQD1, A0A5S9Y630
      Conserved Domains (3) summary
      sd00033
      Location:216 → 243
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13943
      Location:13 → 109
      WPP; WPP domain
      cl39015
      Location:183 → 450
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M651.2

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