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    AFO Plant-specific transcription factor YABBY family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819127, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AFO
    Official Full Name
    Plant-specific transcription factor YABBY family protein
    Primary source
    TAIR:AT2G45190
    Locus tag
    AT2G45190
    See related
    Araport:AT2G45190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABNORMAL FLORAL ORGANS; ABNORMAL FLORAL ORGANS PROTEIN; F4L23.30; FIL; FILAMENTOUS FLOWER; YAB1; YABBY1
    Summary
    Encodes a member of the YABBY family of transcriptional regulators that is involved in abaxial cell type specification in leaves and fruits. YAB1 acts in a non-cell autonomous fashion within the meristem to affect phyllotactic patterning. The non-autonomous effect on the central region of the meristem is mediated through the activity if Lateral Suppressor (LAS).
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    Genomic context

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    See AFO in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (18628252..18630779, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene AUTOPHAGY 8E Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene golgi snare 12 Neighboring gene SAUR-like auxin-responsive protein family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FILAMENTOUS FLOWER controls the formation and development of arabidopsis inflorescences and floral meristems. Sawa S, et al. Plant Cell, 1999 Jan. PMID 9878633, Free PMC Article
    2. FILAMENTOUS FLOWER, a meristem and organ identity gene of Arabidopsis, encodes a protein with a zinc finger and HMG-related domains. Sawa S, et al. Genes Dev, 1999 May 1. PMID 10323860, Free PMC Article
    3. FILAMENTOUS FLOWER controls lateral organ development by acting as both an activator and a repressor. Bonaccorso O, et al. BMC Plant Biol, 2012 Oct 1. PMID 23025792, Free PMC Article
    4. The Arabidopsis FILAMENTOUS FLOWER gene is required for flower formation. Chen Q, et al. Development, 1999 Jun. PMID 10331982
    5. A novel allele of FILAMENTOUS FLOWER reveals new insights on the link between inflorescence and floral meristem organization and flower morphogenesis. Lugassi N, et al. BMC Plant Biol, 2010 Jun 28. PMID 20584289, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BREVIPEDICELLUS (BP) encodes a class-I KNOTTED1-like homeobox (KNOX) transcription factor. FIL acts to oppose KNOX1 gene function through a complex regulatory network that involves changes in secondary metabolites and auxin.
      Title: A novel Filamentous Flower mutant suppresses brevipedicellus developmental defects and modulates glucosinolate and auxin levels.
    2. JAZ3 interacts with YABs to attenuate their transcriptional function.
      Title: FILAMENTOUS FLOWER Is a Direct Target of JAZ3 and Modulates Responses to Jasmonate.
    3. FIL functions as a transcriptional activator in plants and that this activity is involved in leaf patterning.
      Title: FILAMENTOUS FLOWER controls lateral organ development by acting as both an activator and a repressor.
    4. Mutation of these YAB and KNOX1 genes together causes nearly complete suppression of bop1 bop2 ectopic organ outgrowth at the morphological and cellular levels.
      Title: Control of Arabidopsis leaf morphogenesis through regulation of the YABBY and KNOX families of transcription factors.
    5. fil-9 allele mutant flowers show a wide range of organ morphological and identity defects.
      Title: A novel allele of FILAMENTOUS FLOWER reveals new insights on the link between inflorescence and floral meristem organization and flower morphogenesis.
    6. FIL/YAB1 was exclusively expressed in trichome cells
      Title: Quantitative expression analysis of selected transcription factors in pavement, basal and trichome cells of mature leaves from Arabidopsis thaliana.
    7. Analysis of FIL truncations revealed that the first 109 residues of the protein are required for LUG/LUH interactions
      Title: YABBYs and the transcriptional corepressors LEUNIG and LEUNIG_HOMOLOG maintain leaf polarity and meristem activity in Arabidopsis.
    8. Results suggest that YAB1 activity stimulates signals from the organs to the meristem via a secondary message or signal cascade, a process essential for organized growth of the SAM.
      Title: Signals derived from YABBY gene activities in organ primordia regulate growth and partitioning of Arabidopsis shoot apical meristems.
    9. AINTEGUMENTA acts in combination with FILAMENTOUS FLOWER to promote organ polarity by up-regulating the expression of the adaxial-specifying HD-ZIP gene PHABULOSA.
      Title: AINTEGUMENTA contributes to organ polarity and regulates growth of lateral organs in combination with YABBY genes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001337117.1
    NM_130082.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within abaxial cell fate specification IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cell fate commitment IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within fruit development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within inflorescence meristem growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within meristem structural organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in polarity specification of adaxial/abaxial axis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of shoot apical meristem development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within specification of floral organ identity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within specification of plant organ position IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Plant-specific transcription factor YABBY family protein
    NP_566037.1
    • ABNORMAL FLORAL ORGANS (AFO); CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), YABBY protein (InterPro:IPR006780); BEST Arabidopsis thaliana protein match is: Plant-specific transcription factor YABBY family protein (TAIR:AT4G00180.1); Has 454 Blast hits to 452 proteins in 126 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 4; Plants - 436; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18628252..18630779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130082.4 → NP_566037.1  Plant-specific transcription factor YABBY family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566037.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22152
      UniProtKB/TrEMBL
      A0A178VSP4, A0A384LM25, Q0V811
      Conserved Domains (1) summary
      pfam04690
      Location:20 → 189
      YABBY; YABBY protein

    2. NM_001337117.1 → NP_001323472.1  Plant-specific transcription factor YABBY family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AX82, A0A7G2EI91
      Conserved Domains (1) summary
      pfam04690
      Location:1 → 125
      YABBY; YABBY protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22152.1

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