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    SPATA31F3 SPATA31 subfamily F member 3 [ Homo sapiens (human) ]

    Gene ID: 100129969, updated on 10-Dec-2024

    Summary

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    Official Symbol
    SPATA31F3provided by HGNC
    Official Full Name
    SPATA31 subfamily F member 3provided by HGNC
    Primary source
    HGNC:HGNC:42673
    See related
    Ensembl:ENSG00000187791 AllianceGenome:HGNC:42673
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FAM205C; FAM205CP
    Summary
    Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis (RPKM 8.5) See more
    Orthologs
    mouse all
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    Genomic context

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    See SPATA31F3 in Genome Data Viewer
    Location:
    9p13.3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (34889066..34895764, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (34908086..34914785, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (34889063..34895761, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene PHD finger protein 24 Neighboring gene SPATA31 subfamily F member 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:34766948-34767450 Neighboring gene SPATA31 subfamily F member 2, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr9:34870473-34870974 Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta pseudogene 6 Neighboring gene glutamate-ammonia ligase pseudogene 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. DNA sequence and analysis of human chromosome 9. Humphray SJ, et al. Nature, 2004 May 27. PMID 15164053, Free PMC Article
    2. The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. Capalbo L, et al. Nat Commun, 2019 Oct 4. PMID 31586073, Free PMC Article
    3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein SPATA31F3
    Names
    FAM205C pseudogene
    family with sequence similarity 205 member C
    family with sequence similarity 205, member C, pseudogene
    protein FAM205C
    protein FAM205CP
    putative family with sequence similarity 205, member C protein
    transmembrane protein C9orf144B pseudogene

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001309426.2 → NP_001296355.1  protein SPATA31F3 isoform a

      See identical proteins and their annotated locations for NP_001296355.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AI125404, AL355377, DB042441, DB454411
      Consensus CDS
      CCDS83358.1
      UniProtKB/Swiss-Prot
      A6NFA0
      Related
      ENSP00000489585.1, ENST00000603640.6
      Conserved Domains (1) summary
      pfam15371
      Location:55 → 136
      DUF4599; Domain of unknown function (DUF4599)

    2. NM_001309427.2 → NP_001296356.1  protein SPATA31F3 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses two alternate in-frame splice sites in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
      Source sequence(s)
      AI125404, AL355377, DB042441
      Consensus CDS
      CCDS83359.1
      UniProtKB/TrEMBL
      A0A0U1RRK5
      Related
      ENSP00000489571.1, ENST00000340783.11
      Conserved Domains (1) summary
      pfam15371
      Location:52 → 118
      DUF4599; Domain of unknown function (DUF4599)

    3. NM_001375894.1 → NP_001362823.1  protein SPATA31F3 isoform c

      Status: VALIDATED

      Source sequence(s)
      AL355377
      Conserved Domains (1) summary
      pfam15371
      Location:52 → 122
      DUF4599; Domain of unknown function (DUF4599)

    RNA

    1. NR_164743.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL355377

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      34889066..34895764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      34908086..34914785 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NG_027513.1: Suppressed sequence

      Description
      NG_027513.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6NFA0.2 GenPept UniProtKB/Swiss-Prot:A6NFA0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials