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    TEC1 Tec1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852377, updated on 2-Nov-2024

    Summary

    Official Symbol
    TEC1
    Official Full Name
    Tec1p
    Primary source
    SGD:S000000287
    Locus tag
    YBR083W
    See related
    AllianceGenome:SGD:S000000287; FungiDB:YBR083W; VEuPathDB:YBR083W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ROC1
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including invasive growth in response to glucose limitation; positive regulation of pseudohyphal growth; and pseudohyphal growth. Located in nucleus. Part of Tec1p-Ste12p-Dig1p complex. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to several human genes including TEAD3 (TEA domain transcription factor 3). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See TEC1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (409169..410629)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene tRNA-Asp Neighboring gene E2 ubiquitin-conjugating protein UBC4 Neighboring gene trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1 Neighboring gene ribosomal 60S subunit protein L19A

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Component Evidence Code Pubs
    part_of Tec1p-Ste12p-Dig1p complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Tec1p
    NP_009639.3
    • Transcription factor targeting filamentation genes and Ty1 expression; Ste12p activation of most filamentation gene promoters depends on Tec1p and Tec1p transcriptional activity is dependent on its association with Ste12p; binds to TCS elements upstream of filamentation genes, which are regulated by Tec1p/Ste12p/Dig1p complex; competes with Dig2p for binding to Ste12p/Dig1p; positive regulator of chronological life span; TEA/ATTS DNA-binding domain family member

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      409169..410629
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178431.3NP_009639.3  TPA: Tec1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009639.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQ82, P18412
      UniProtKB/TrEMBL
      A6ZL29, B3LN69, B5VE46, G2W989, N1PAS4
      Conserved Domains (1) summary
      smart00426
      Location:127192
      TEA; TEA domain