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    Tmem223 transmembrane protein 223 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690285, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tmem223provided by RGD
    Official Full Name
    transmembrane protein 223provided by RGD
    Primary source
    RGD:1582829
    See related
    EnsemblRapid:ENSRNOG00000019266 AllianceGenome:RGD:1582829
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable mitochondrial ribosome binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be active in mitochondrial inner membrane. Orthologous to human TMEM223 (transmembrane protein 223). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Thymus (RPKM 291.8), Kidney (RPKM 286.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tmem223 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (215097835..215099196)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (205668716..205670077)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (224970807..224972168)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene syntaxin 5 Neighboring gene nuclear RNA export factor 1 Neighboring gene transmembrane protein 179B Neighboring gene interferon-induced transmembrane protein 2-like Neighboring gene TATA-box binding protein associated factor 6 like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mitochondrial ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191104.1NP_001178033.1  transmembrane protein 223

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      D4AC93
      Related
      ENSRNOP00000026141.2, ENSRNOT00000026141.6
      Conserved Domains (1) summary
      pfam14640
      Location:32197
      TMEM223; Transmembrane protein 223

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      215097835..215099196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)