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    Tes testin LIM domain protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500040, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tesprovided by RGD
    Official Full Name
    testin LIM domain proteinprovided by RGD
    Primary source
    RGD:1566346
    See related
    EnsemblRapid:ENSRNOG00000051952 AllianceGenome:RGD:1566346
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of cell population proliferation. Predicted to be located in cytosol; focal adhesion; and plasma membrane. Predicted to be part of protein-containing complex. Orthologous to human TES (testin LIM domain protein). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 777.8), Uterus (RPKM 251.4) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Tes in Genome Data Viewer
    Location:
    4q22
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (46331257..46369782)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (45365304..45403829)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (44321883..44360407)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486669 Neighboring gene uncharacterized LOC120102238 Neighboring gene uncharacterized LOC102550644 Neighboring gene caveolin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    testin
    Names
    testis derived transcript

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039344.2NP_001034433.1  testin

      See identical proteins and their annotated locations for NP_001034433.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129069
      UniProtKB/Swiss-Prot
      Q2LAP6
      UniProtKB/TrEMBL
      A0A8I6AV73, A6IE14
      Related
      ENSRNOP00000070338.1, ENSRNOT00000091095.3
      Conserved Domains (4) summary
      cd09413
      Location:234291
      LIM1_Testin; The first LIM domain of Testin
      cd09416
      Location:297352
      LIM2_Testin; The second LIM domain of Testin
      cd09419
      Location:359417
      LIM3_Testin; The third LIM domain of Testin
      cd09829
      Location:109196
      PET_testin; The PET domain of Testin

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      46331257..46369782
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)