Poglut3 protein O-glucosyltransferase 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Poglut3provided by RGD
Official Full Name: protein O-glucosyltransferase 3provided by RGD
Primary source: RGD:1562027
See related: EnsemblRapid:ENSRNOG00000007177 AllianceGenome:RGD:1562027
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Kdelc2
Summary: Predicted to enable UDP-glucosyltransferase activity and UDP-xylosyltransferase activity. Predicted to be involved in protein O-linked glycosylation via serine. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in endomembrane system. Orthologous to human POGLUT3 (protein O-glucosyltransferase 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Heart (RPKM 177.7), Lung (RPKM 141.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q24

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (62673811..62691606)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (53777614..53795404)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (57964988..57982605)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH128975 (e-PCR)
- UniSTS:212283

BI293078 (e-PCR)
- UniSTS:245600

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables EGF-domain serine glucosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables EGF-domain serine xylosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables UDP-glucosyltransferase activity	ISO Inferred from Sequence Orthology more info
enables UDP-glucosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables UDP-xylosyltransferase activity	ISO Inferred from Sequence Orthology more info
enables UDP-xylosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables glucosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein O-linked glycosylation via serine	ISO Inferred from Sequence Orthology more info
involved_in protein O-linked glycosylation via serine	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum lumen	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein O-glucosyltransferase 3

Names: KDEL (Lys-Asp-Glu-Leu) containing 2; KDEL motif containing 2; KDEL motif-containing protein 2; protein O-xylosyltransferase POGLUT3

NP_001020294.3

EC 2.4.2.26

XP_063121533.1

EC 2.4.2.26

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.