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    Ms4a18 membrane-spanning 4-domains, subfamily A, member 18 [ Mus musculus (house mouse) ]

    Gene ID: 76002, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ms4a18provided by MGI
    Official Full Name
    membrane-spanning 4-domains, subfamily A, member 18provided by MGI
    Primary source
    MGI:MGI:1923252
    See related
    Ensembl:ENSMUSG00000094584 AllianceGenome:MGI:1923252
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5033428B15Rik
    Summary
    Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MS4A18 (membrane spanning 4-domains A18). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in large intestine adult (RPKM 56.0), duodenum adult (RPKM 24.1) and 1 other tissue See more
    Orthologs
    human all
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    Genomic context

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    See Ms4a18 in Genome Data Viewer
    Location:
    19 A; 19 7.5 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10974388..10995390, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10997024..11018026, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene membrane-spanning 4-domains, subfamily A, member 10 Neighboring gene STARR-seq mESC enhancer starr_45563 Neighboring gene STARR-positive B cell enhancer ABC_E11021 Neighboring gene STARR-positive B cell enhancer mm9_chr19:11054242-11054543 Neighboring gene membrane-spanning 4-domains, subfamily A, member 15 Neighboring gene predicted gene 28347 Neighboring gene expressed sequence AW112010

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
    5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    membrane-spanning 4-domains subfamily A member 18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001251849.1 → NP_001238778.1  membrane-spanning 4-domains subfamily A member 18

      See identical proteins and their annotated locations for NP_001238778.1

      Status: VALIDATED

      Source sequence(s)
      AC148991, AK017199
      Consensus CDS
      CCDS57137.1
      UniProtKB/TrEMBL
      J3QN01
      Related
      ENSMUSP00000136529.2, ENSMUST00000177684.3
      Conserved Domains (1) summary
      pfam04103
      Location:152 → 233
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      10974388..10995390 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527428.2 → XP_006527491.1  membrane-spanning 4-domains subfamily A member 18 isoform X1

      See identical proteins and their annotated locations for XP_006527491.1

      UniProtKB/TrEMBL
      J3QN01
      Conserved Domains (1) summary
      pfam04103
      Location:152 → 233
      CD20; CD20-like family

    2. XM_006527429.2 → XP_006527492.1  membrane-spanning 4-domains subfamily A member 18 isoform X2

      Conserved Domains (1) summary
      pfam04103
      Location:155 → 191
      CD20; CD20-like family
    Nucleotide Protein Strain
    Heading Accession and Version

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