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    mus304 mutagen-sensitive 304 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40003, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mus304provided by FlyBase
    Official Full Name
    mutagen-sensitive 304provided by FlyBase
    Primary source
    FLYBASE:FBgn0002901
    Locus tag
    Dmel_CG7347
    See related
    AllianceGenome:FB:FBgn0002901
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.82; atrip; ATRIP; CG7347; Dmel\CG7347; mus(3)304; mus-304; Mus304
    Summary
    Involved in several processes, including DNA integrity checkpoint signaling; DNA metabolic process; and female meiosis chromosome segregation. Located in cytoplasm. Is expressed in nurse cell; oocyte; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mus304 in Genome Data Viewer
    Location:
    75B9-75B10; 3-45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (18109814..18112847)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (18102914..18105947)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S26 Neighboring gene RNA polymerase III subunit D Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A method for assaying the sensitivity of Drosophila replication checkpoint mutants to anti-cancer and DNA-damaging drugs. Radcliffe CM, et al. Genome, 2002 Oct. PMID 12416620
    2. Mutants partially defective in excision repair at five autosomal loci in Drosophila melanogaster. Boyd JB, et al. Chromosoma, 1981. PMID 6785044
    3. Involvement of DNA Repair Genes and System of Radiation-Induced Activation of Transposons in Formation of Transgenerational Effects. Yushkova E. Front Genet, 2020. PMID 33329741, Free PMC Article
    4. Cell-cycle checkpoint kinases: checking in on the cell cycle. Walworth NC. Curr Opin Cell Biol, 2000 Dec. PMID 11063934
    5. Re-evaluation of excision repair in the mus304, mus306 and mus308 mutants of Drosophila. Harris PV, et al. Mutat Res, 1993 Jan. PMID 7677944

    See all (71) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in DNA damage checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA damage checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in female meiosis chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in female meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in imaginal disc development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in mitotic DNA replication checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of syncytial blastoderm mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to radiation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in telomere maintenance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mutagen-sensitive 304
    Names
    ATR-interacting protein
    CG7347-PA
    mus304-PA
    mutagen sensitive 304

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      18109814..18112847
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079411.4 → NP_524135.3  mutagen-sensitive 304 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524135.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B6UXA1, B6UXA5, B6UXA6, B6UXA7, B6UXA8, B6UXA9, B6UXB0, B6UXB1, B6UXB2, B6UXB3, B6UXB4, B6UXB5, B6UXB6, B6UXB7, B6UXB8, B6UXB9, B6UXC0, B6UXC1, B6UXC2, B6UXC3, B6UXC4, B6UXC5, B6UXC6, B6UXC7, B6UXC8, B6UXC9, B6UXD0, B6UXD1, Q9VVN4
      Related
      FBpp0074888
      Conserved Domains (1) summary
      cl21478
      Location:178 → 303
      ATP-synt_B; ATP synthase B/B' CF(0)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVN4.2 Q9VVN4

    Gene LinkOut

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