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    dpr17 defective proboscis extension response 17 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41470, updated on 27-Dec-2024

    Summary

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    Official Symbol
    dpr17provided by FlyBase
    Official Full Name
    defective proboscis extension response 17provided by FlyBase
    Primary source
    FLYBASE:FBgn0051361
    Locus tag
    Dmel_CG31361
    See related
    AllianceGenome:FB:FBgn0051361
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14737; CG14738; CG31361; CT34531; Dmel\CG31361; Dpr-17; Dpr17
    Summary
    Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. Is expressed in several structures, including amnioserosa; embryonic/larval oenocyte; gland; larval ventral nerve cord; and somatic trunk mesoderm derivative. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dpr17 in Genome Data Viewer
    Location:
    87A8-87A9; 3-51 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12094876..12111420)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (7920598..7937142)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ATPase 8B Neighboring gene transfer RNA:Lysine-TTT 2-5 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster. Cridland JM, et al. Genetics, 2023 May 4. PMID 36869688, Free PMC Article
    2. Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms. Peng J, et al. Elife, 2018 Mar 7. PMID 29513217, Free PMC Article
    3. Transneuronal Dpr12/DIP-δ interactions facilitate compartmentalized dopaminergic innervation of Drosophila mushroom body axons. Bornstein B, et al. EMBO J, 2021 Jun 15. PMID 33847376, Free PMC Article
    4. The transcription factor FoxK participates with Nup98 to regulate antiviral gene expression. Panda D, et al. mBio, 2015 Apr 7. PMID 25852164, Free PMC Article
    5. Multiple Niche Compartments Orchestrate Stepwise Germline Stem Cell Progeny Differentiation. Tu R, et al. Curr Biol, 2021 Feb 22. PMID 33357404, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    defective proboscis extension response 17
    Names
    CG31361-PA
    CG31361-PB
    CG31361-PC
    CG31361-PD
    CG31361-PE
    dpr17-PA
    dpr17-PB
    dpr17-PC
    dpr17-PD
    dpr17-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      12094876..12111420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169451.2 → NP_731670.1  defective proboscis extension response 17, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731670.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SWT7, Q9VGD3
      Related
      FBpp0082016
      Conserved Domains (3) summary
      smart00408
      Location:524 → 605
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:521 → 612
      IG_like; Immunoglobulin like
      cl11960
      Location:415 → 507
      Ig; Immunoglobulin domain

    2. NM_001300368.1 → NP_001287297.1  defective proboscis extension response 17, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287297.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SWT7, Q9VGD3
      Conserved Domains (3) summary
      smart00408
      Location:524 → 605
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:521 → 612
      IG_like; Immunoglobulin like
      cl11960
      Location:415 → 507
      Ig; Immunoglobulin domain

    3. NM_001300369.1 → NP_001287298.1  defective proboscis extension response 17, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287298.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NNA1, Q9VGD2
      Conserved Domains (3) summary
      smart00408
      Location:368 → 449
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:365 → 456
      IG_like; Immunoglobulin like
      cl11960
      Location:259 → 351
      Ig; Immunoglobulin domain

    4. NM_001144567.2 → NP_001138039.1  defective proboscis extension response 17, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138039.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NNA1, Q9VGD2
      Conserved Domains (3) summary
      smart00408
      Location:368 → 449
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:365 → 456
      IG_like; Immunoglobulin like
      cl11960
      Location:259 → 351
      Ig; Immunoglobulin domain

    5. NM_169452.3 → NP_731671.1  defective proboscis extension response 17, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731671.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NNA1, Q9VGD2
      Related
      FBpp0082017
      Conserved Domains (3) summary
      smart00408
      Location:368 → 449
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:365 → 456
      IG_like; Immunoglobulin like
      cl11960
      Location:259 → 351
      Ig; Immunoglobulin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SWT7 Q8SWT7
    Q9VGD2 Q9VGD2
    Q9VGD3 Q9VGD3

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