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    Ir56a Ionotropic receptor 56a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246471, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Ir56aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 56aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050125
    Locus tag
    Dmel_CG30125
    See related
    AllianceGenome:FB:FBgn0050125
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    56a; CG30125; DmelIR56a; Dmel\CG30125; IR56a
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in gustatory receptor neurons; labellar taste bristle; labral sense organ neurons; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir56a in Genome Data Viewer
    Location:
    56B3-56B3; 2-88 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19094267..19096174, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14981772..14983679, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Glutathione peroxidase-like Neighboring gene uncharacterized protein Neighboring gene 5-hydroxytryptamine (serotonin) receptor 1A Neighboring gene uncharacterized protein Neighboring gene brother of tout-velu

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Diversity of Internal Sensory Neuron Axon Projection Patterns Is Controlled by the POU-Domain Protein Pdm3 in Drosophila Larvae. Qian CS, et al. J Neurosci, 2018 Feb 21. PMID 29367405, Free PMC Article
    2. A receptor and neuron that activate a circuit limiting sucrose consumption. Joseph RM, et al. Elife, 2017 Mar 23. PMID 28332980, Free PMC Article
    3. Ionotropic receptors mediate nitrogenous waste avoidance in Drosophila melanogaster. Dhakal S, et al. Commun Biol, 2021 Nov 12. PMID 34773080, Free PMC Article
    4. Calcium Taste Avoidance in Drosophila. Lee Y, et al. Neuron, 2018 Jan 3. PMID 29276056, Free PMC Article
    5. Candidate ionotropic taste receptors in the Drosophila larva. Stewart S, et al. Proc Natl Acad Sci U S A, 2015 Apr 7. PMID 25825777, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 56a
    Names
    CG30125-PA
    Ir56a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19094267..19096174 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166323.1 → NP_725850.1  ionotropic receptor 56a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725850.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBG7
      Related
      FBpp0085779, FBtr0086595
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBG7 A1ZBG7

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